MIYAGAWA Atsushi

写真a

Affiliation Department

Department of Life Science and Applied Chemistry
Department of Life Science and Applied Chemistry

Title

Associate Professor

Contact information

Contact information

Homepage

http://www.ach.nitech.ac.jp/~organic/yamamura/toppage.html

External Link

Degree

  • Doctor (Engineering) ( The University of Tokyo )

Research Areas

  • Nanotechnology/Materials / Bio chemistry

  • Nanotechnology/Materials / Structural organic chemistry and physical organic chemistry

  • Life Science / Bioorganic chemistry

  • Life Science / Biomaterials

  • Nanotechnology/Materials / Polymer chemistry

From School

  • Saitama University   Faculty of Engineering   Department of Functional Materials Science   Graduated

    - 2001.03

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    Country:Japan

From Graduate School

  • The University of Tokyo   Graduate School, Division of Engineering   Department of Chemistry and Biotechnology   Doctor's Course   Completed

    - 2006.03

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    Country:Japan

  • The University of Tokyo   Graduate School, Division of Engineering   Department of Chemistry and Biotechnology   Doctor's Course   Completed

    - 2003.03

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    Country:Japan

External Career

  • 独立行政法人理化学研究所 基幹研究所 伊藤細胞制御化学研究室   協力研究員

    2007.04 - 2009.03

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    Country:Japan

Professional Memberships

  • FCCA

    2017.04

  • 日本農芸化学会

    2015.01

  • TheJapanese Society Carbohydrate Research

    2009.04

  • The Chemical Society of Japan

  • 高分子学会

 

Research Career

  • タンパク質分解誘導剤の開発

    The Other Research Programs  

    Project Year: 2021.03

  • 高機能性糖鎖を利用した抗菌性高分子の開発

    The Other Research Programs  

    Project Year: 2018.04

  • 病原性物質を中和する糖鎖材料の開発と評価

    (not selected)  

    Project Year: 2013.04

  • 糖転移酵素阻害剤の開発

    (not selected)  

    Project Year: 2012.04

Papers

  • Preparation of β-1, 3-glucan mimics via modification of polymer backbone, and evaluation of cytokine production using the polymer library in immune activation Reviewed International journal

    Miyagawa, A., Yamamoto, N., Ohno, A., Yamamura, H

    International Journal of Biological Macromolecules   264   130546   2024.04

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1016/j.ijbiomac.2024.130546

  • Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase Reviewed International coauthorship International journal

    Beatriz Piniello, Javier Macías-León, Shun Miyazaki, Ana García-García, Ismael Compañón, Mattia Ghirardello, Víctor Taleb, Billy Veloz, Francisco Corzana, Atsushi Miyagawa, Carme Rovira, Ramon Hurtado-Guerrero

    Nature Communications   14   5785   2023.09

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1038/s41467-023-41238-1

    Other Link: https://www.nature.com/articles/s41467-023-41238-1

  • Identification of a tomato UDP-arabinosyltransferase for airborne volatile reception Reviewed International journal

    Koichi Sugimoto, Eiichiro Ono, Tamaki Inaba, Takehiko Tsukahara, Kenji Matsui, Manabu Horikawa, Hiromi Toyonaga, Kohki Fujikawa, Tsukiho Osawa, Shunichi Homma, Yoshikazu Kiriiwa, Ippei Ohmura, Atsushi Miyagawa, Hatsuo Yamamura, Mikio Fujii, Rika Ozawa, Bunta Watanabe, Kenji Miura, Hiroshi Ezura, Toshiyuki Ohnishi, Junji Takabayashi

    14   677   2023.02

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1038/s41467-023-36381-8

    Other Link: https://www.nature.com/articles/s41467-023-36381-8

  • One-step Synthesis of Sugar Nucleotides Reviewed International journal

    Atsushi Miyagawa, Sanami Toyama, Ippei Ohmura, Shun Miyazaki, Takeru Kamiya, Hatsuo Yamamura

    The Journal of Organic Chemistry   85 ( 23 )   15645 - 15651   2020.11

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society  

    DOI: https://doi.org/10.1021/acs.joc.0c01943

  • Facile synthesis of β-1,3-glucan disaccharides using acyl protected glycosyl donors and acceptors prepared from 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose Invited Reviewed

    Atsushi Miyagawa, Ryusuke Tomita, Hatsuo Yamamura

    TRENDS IN ORGANIC CHEMISTRY   24   69 - 78   2024.05

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Synthesis of cyclodextrin dimers via Diels–Alder reaction Reviewed International journal

    Atsushi Miyagawa,Takuya Hasegawa, Hatsuo Yamamura

    Synthetic Communications   53 ( 22 )   1878 - 1885   2023.09

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1080/00397911.2023.2254427

  • Anti-bacterial β-cyclodextrin derivatives inspired by the antimicrobial peptide polymyxin in order to better understand the role of single hydrophobic chain tail in selective anti-bacterial activity Reviewed International journal

    Hatsuo Yamamura, Masashi Owaki, Kana Isshiki, Yukari Ishihara, Hisato Kato, Takashi Katsu, Kazufumi Masuda, Kayo Osawac, Atsushi Miyagawa

    New Journal of Chemistry   47   10921 - 10929   2023.04

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1039/D3NJ01028G

  • Synthesis of antimicrobial polymers with mannose residues for binding to the FimH adhesin of Escherichia coli Reviewed International journal

    Atsushi Miyagawa, Shinya Ohno, Hatsuo Yamamura

    61 ( 4 )   277 - 288   2023.02

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:John Wiley & Sons, Inc.  

    DOI: https://doi.org/10.1002/pol.20220540

  • Protecting-group-free glycosylation of phosphatidic acid in aqueous media Reviewed International journal

    Koki Kano, Nozomi Ishii, Atsushi Miyagawa, Hiroaki Takeda, Yoshio Hirabayashi, Hiroyuki Kamiguchi, Peter Greimel, Ichiro Matsuo

    Organic & Biomolecular Chemistry   21   2138 - 2142   2023.02

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1039/D2OB02173K

  • UDP-glucose, cereblon-dependent proinsulin degrader Reviewed International journal

    Jaeyong Cho, Atsushi Miyagawa, Kazuki Yamaguchi, Wakana Abe, Yoji Tsugawa, Hatsuo Yamamura, Takeshi Imai

    Scientific Reports   12   14568   2022.08

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-022-18902-5

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Misc

  • Stereoselective Glycosylation by Ether Protecting Groups Invited Reviewed International journal

    Atsushi Miyagawa

    31 ( 182 )   E109 - E110   2019.07

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:FCCA  

    DOI: 10.4052/tigg.1964.6E

  • エーテル保護基による立体選択的グリコシル化 Invited Reviewed International journal

    Atsushi Miyagawa

    31 ( 182 )   J109 - J110   2019.07

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:FCCA  

    DOI: 10.4052/tigg.1964.6J

  • Chemical Synthesis of β-(1,3)-Glucan Oligosaccharide and Its Application Invited Reviewed International journal

    Atsushi Miyagawa

    30 ( 175 )   E117 - E127   2018.07

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:FCCA  

    DOI: https://doi.org/10.4052/tigg.1706.1E

  • Cationic Amphiphilic Oligosaccharides as Antibiotics Invited Reviewed International journal

    Atsushi Miyagawa

    30 ( 175 )   E137 - E138   2018.07

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:FCCA  

  • β-(1,3)-グルカンオリゴ糖の化学合成とその応用 Invited Reviewed

    宮川 淳

    30 ( 175 )   J91 - J101   2018.07

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (international conference proceedings)  

  • 抗菌剤としてのカチオン型両親媒性オリゴ糖 Invited Reviewed

    宮川 淳

    30 ( 175 )   J113 - J114   2018.07

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 名古屋工業大学「化学公開セミナー」

    宮川淳

    2011.06

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (international conference proceedings)   Publisher:日本化学会  

Presentations

  • Synthesis of Sugar Nucleotides in One-Step Reaction Invited International conference

    Atsushi Miyagawa

    2022.06 

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    Event date: 2022.06

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Functionalization of Selective Antimicrobial Activity to Antimicrobial Polymers Using Sugar Ligands Invited International conference

    Atsushi Miyagawa

    The 7th International Conference on Materials Engineering and Nanotechnology  2023.11  ICTEO

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    Event date: 2023.11

    Language:English   Presentation type:Oral presentation (invited, special)  

  • 疎水性の調節により高い抗菌性を目指した2種類のアルキルアミノ基を持つシクロデキ ストリン誘導体

    山村初雄、早野匠真、宮川淳

    第39回シクロデキストリンシンポジウム  2023.09  シクロデキストリン学会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  • 一段階反応による種々の糖ヌクレオチドの効率的合成

    藤原 亘汰、神川 早希、山村 初雄、宮川  淳

    第 7 回 FCCA シンポジウム グライコサイエンス若手フォーラム 2023  2023.09  グライコサイエンス若手の会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鳥取大学  

  • ベロ毒素中和機能を有するグロボ 3 糖を導入した抗菌ポリマーの合成と ポリマー構造の違いによる抗菌性評価

    宮川  淳、寺島 萌乃、山村 初雄

    第 7 回 FCCA シンポジウム グライコサイエンス若手フォーラム 2023  2023.09  グライコサイエンス若手の会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鳥取大学  

  • 糖ヌクレオチドの一段階合成反応の最適化

    藤原 亘汰、神川 早希、山村 初雄、宮川  淳

    第42回日本糖質学会年会  2023.09  日本糖質学会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鳥取  

  • β-グルカン模倣高分子ライブラリー構築とDectin-1 の親和性と免疫活性化の相関研究

    宮川  淳、山本 菜未、大野 綾音、山村 初雄

    第42回日本糖質学会年会  2023.09  日本糖質学会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鳥取  

  • グロボ3糖を導入した抗菌ポリマーの合成と抗菌性評価

    宮川  淳、寺島 萌乃、山村 初雄

    第42回日本糖質学会年会  2023.09  日本糖質学会

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    Event date: 2023.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:鳥取  

  • 高分子主鎖の修飾によるβ-グルカン模倣高分子群の合成およびDectin-1に対する親和性評価

    宮川 淳、山本菜未、大野綾音、山村初雄

    糖鎖科学中部拠点 第18回 「若手の力」フォーラム  2023.01  糖鎖科学中部拠点

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    Event date: 2023.01

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名城大学  

  • 糖尿病治療のためのインスリン前駆体であるプロインスリンの分解誘導および阻害分子の開発

    宮川 淳、安部 和佳奈、Jaeyong Cho、今井 剛、山口 一貴、山村 初雄

    糖鎖科学中部拠点 第18回 「若手の力」フォーラム  2023.01  糖鎖科学中部拠点

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    Event date: 2023.01

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名城大学  

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Industrial Property Rights

  • 毒素やウイルスを除去する糖鎖ポリマー固定化フィルター

    -

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    Application no:特許公開2008-229435 

    Country of applicant:Domestic   Country of acquisition:Domestic

  • 病原性微粒子吸着性中空糸及び病原性微粒子除去装置

    -

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    Application no:特許公開2003-135596 

    Country of applicant:Domestic   Country of acquisition:Domestic

Awards

  • Best Oral Presentation Award

    2020.11   PCM 2020  

    Atsushi Miyagawa

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • 第6回FCCAシンポジウム・グライコサイエンス若手フォーラム2019 ポスター賞

    2019.08   グライコサイエンス若手の会  

    宮川淳, 宮崎舜, 山村初雄

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 第6回FCCAシンポジウム・グライコサイエンス若手フォーラム2019 講演賞

    2019.08   グライコサイエンス若手の会  

    宮川淳, 大野綾音, 金野克博, 山村初雄

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 第50回東海化学工業会賞(学術賞)

    2015.05   東海化学工業会  

    宮川 淳

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    Award type:Award from publisher, newspaper, foundation, etc.  Country:Japan

  • 日本糖質学会ポスター賞

    2013.12   日本糖質学会  

    宮川 淳

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 優秀講演賞

    2009.04   -  

    -

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    Country:Japan

Scientific Research Funds Acquisition Results

  • βグルカンを模倣した高分子の合成とそれを用いた免疫活性化に必要な分子構造の解明

    2020.04 - 2023.03

    科学研究費補助金  基盤研究(C)

    宮川 淳

Other External Funds

  • 糖複合体医薬品を自在に改変するための糖ヌクレオチドの簡便合成

    2023.08 - 2024.07

    公益財団法人内藤科学技術振興財団 

    宮川 淳

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000 ( Direct Cost: \970000 、 Indirect Cost:\30000 )

  • 腸管出血性大腸菌O157感染症の根本的な治療に向けた、O157に対する抗菌性と菌体内毒素の中和能をクラスター化した高分子薬剤の開発

    2023.04 - 2025.03

    公益財団法人小笠原敏晶記念財団  一般研究助成 

    宮川淳

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\5000000

  • 免疫調整分子Dectin-1のアンタゴニストである水溶性βグルカンの集積化による免疫活性化分子の開発

    2023.04 - 2024.03

    公益財団法人天野工業技術研究所 

    宮川淳、堀 聡真

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1500000 ( Direct Cost: \1455000 、 Indirect Cost:\45000 )

  • 免疫調節薬レナリドミドの鏡像異性体分離とそれを利用したガン治療のためのタンパク質分解誘導剤の開発

    2022.04 - 2024.03

    公益財団法人 立松財団  特別研究助成 

    宮川 淳

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3000000 ( Direct Cost: \2910000 、 Indirect Cost:\90000 )

  • 真菌検出に利用するための競合的評価を可能にする糖鎖プローブの合成

    2022.04 - 2023.03

    公益財団法人 小柳財団  2022年度研究助成金 

    宮川 淳

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000 ( Direct Cost: \1000000 )

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Past of Cooperative Research

  • 画期的医薬品創出のためのシクロデキストリン誘導体合成

    2023.09 - 2024.08

    株式会社サイディン  Collaboration in College 

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    Grant amount:\650000 ( Direct Cost: \500000 、 Indirect Cost:\150000 )

  • undruggableな標的タンパク質分解誘導剤の開発

    2021.04 - 2026.03

    Collaboration in Japan 

    宮川 淳

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    Authorship:Principal investigator 

 

Teaching Experience

  • 基礎物質科学

    2021.04 Institution:Nagoya Institute of Technology

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    Level:Undergraduate (liberal arts) 

  • 有機化学I

    2019.04 Institution:Nagoya Institute of Technology

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    Level:Undergraduate (specialized) 

  • 生物有機化学特論

    2019.04 Institution:Nagoya Institute of Technology

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    Level:Postgraduate 

 

Committee Memberships

  • 東海化学工業会   編集委員  

    2024.04   

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    Committee type:Academic society

  • 中部化学関係学協会支部連合協議会   実行委員  

    2024.03 - 2025.03   

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    Committee type:Academic society

  •   論文編集委員  

    2023.11   

  • シクロデキストリン学会   第39回シクロデキストリンシンポジウム実行委員会  

    2023.02 - 2023.09   

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    Committee type:Academic society

Social Activities

  • 糖の機能を解明して、更なる可能性を広げる

    Role(s): Contribution

    国立大学55工学系学部長会議  なんでも探検隊  2023.11

  • 知の探究講座

    Role(s): Lecturer

    2023.07

Media Coverage

  • 植物間コミュニケーションによって,植物が将来起こり得る被害から身を守る仕組みを解明 Internet

    日本経済新聞  https://www.nikkei.com/article/DGXZRSP650151_X20C23A2000000/  2023.02