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Affiliation Department |
電気・機械工学科 機械工学分野
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Title |
Associate Professor |
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External Link |
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UJIHARA Yoshihiro
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Degree
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博士（工学） ( 2011.03 大阪大学 )
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修士（工学） ( 2008.03 大阪大学 )
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学士（工学） ( 2006.03 大阪大学 )
From School
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Osaka University Faculty of Engineering Science Graduated
2002.04 - 2006.03
Country：Japan
From Graduate School
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Osaka University Graduate School, Division of Engineering Science Doctor's Course Completed
2008.04 - 2011.03
Country：Japan
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Osaka University Graduate School, Division of Engineering Science Master's Course Completed
2006.04 - 2008.03
Country：Japan
External Career
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Kawasaki Medical School Lecturer
2018.04 - 2018.09
Country：Japan
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Kawasaki Medical School Assistant Professor
2011.04 - 2018.03
Country：Japan
Professional Memberships
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日本進化学会
2020.09
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生物物理学会(Biophysical Society)
2017.10
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日本生理学会
2013.10
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日本生体医工学会
2011.04
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日本機械学会
2006.07
Papers
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Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure Reviewed International journal
Yoshihiro Ujihara, Motoi Kanagawa, Satoshi Mohri, Satomi Takatsu, Kazuhiro Kobayashi, Tatsushi Toda, Keiji Naruse, Yuki Katanosaka
Nature Communications 10 1 - 17 2019.12
Language：English Publishing type：Research paper (scientific journal)
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Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodeling Reviewed International journal
Ujihara Y, Iwasaki K, Takatsu S, Hashimoto K, Naruse K, Mohri S, Katanosaka Y
Cardiovascular Research 111 ( 4 ) 348 - 361 2016.09
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1093/cvr/cvw113
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Proposed spring network cell model based on a minimum energy concept Reviewed International journal
Ujihara Y, Nakamura M, Miyazaki H, Wada S
Annals of Biomedical Engineering 38 ( 4 ) 1539 - 1538 2010.04
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Relationships among capillary refill time, peripheral blood flow rate, and fingertip temperature: advances in peripheral artery contractility diagnosis Reviewed International journal
Sorataro Shibata, Yoshihiro Ujihara, Masanori Nakamura, and Shukei Sugita
Journal of Biomechanical Engineering 147 ( 2 ) 021005 2025.02
Authorship：Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1115/1.4067209
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Phenotypic Plasticity of Vascular Smooth Muscle Cells in Aortic Dissection: Insights from Ex Vivo Flow Exposure Studies Reviewed International journal
Iwata S, Ujihara Y, Sugita S, Nakamura M
Journal of Biorheology 39 2024.12
Language：English Publishing type：Research paper (scientific journal)
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Probing mechanical properties through acoustic impedance in cultured smooth muscle cells with cytoskeletal disruption using scanning acoustic microscopy Reviewed International journal
Yoshihiro Ujihara, Shota Watanabe, Shinri Morodomi, Shukei Sugita, Masanori Nakamura
Journal of Biorheology 39 2024.12
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
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Stress Fiber Strain is Zero in Normal Aortic Smooth Muscle, Elevated in Hypertensive Stretch, and Minimal in Wall Thickening Rats Reviewed
14 29731 2024.11
Language：English Publishing type：Research paper (scientific journal)
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Finite element analysis and computational fluid dynamics to elucidate the mechanism of distal stent graft-induced new entry after frozen elephant trunk technique Reviewed International journal
Morodomi S, Okamura H, Ujihara Y, Sugita S, Nakamura M
European Journal of Cardio-Thoracic Surgery 2024.10
Language：English Publishing type：Research paper (scientific journal)
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Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics Reviewed International journal
Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri
Scientific Reports 14 ( 1 ) 13727 2024.06
Language：English Publishing type：Research paper (scientific journal)
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Mathematical modeling and experimental analysis of the relationship between ventricular size and diastolic function of trabecular ventricles Reviewed International journal
Megumi Ito, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura
37 ( 2 ) 96 - 104 2023.11
Language：English Publishing type：Research paper (scientific journal)
Books and Other Publications
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A mechanical cell model and its application to cellular biomechanics
Ujihara Y, Nakamura M, Wada S（ Role： Joint author）
In Tech 2011
Language：eng Book type：Scholarly book
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Effects of cytoskeletal structures on elastic and viscoelastic properties of cells in soft tissues
Matsumoto T, Nagayama K, Miyazaki H, Ujihara Y（ Role： Joint author）
World Scientific Publishers 2007
Language：eng Book type：Scholarly book
Misc
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Predictive Methods for Thrombus Formation in the Treatment of Aortic Dissection and Cerebral Aneurysms: A Comprehensive Review Reviewed
Kenji Komiya, Shuta Imada, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura
Bioengineering 11 ( 9 ) 871 2024.08
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
DOI： 10.3390/bioengineering11090871
Other Link： https://www.mdpi.com/2306-5354/11/9/871
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心筋細胞の特殊膜構造から探る哺乳類と鳥類の心臓の違い： カルシウム濃度管理と心臓の「しなやかさ」 Invited Reviewed
氏原 嘉洋
49 ( 2 ) 82 - 86 2024.03
Authorship：Lead author, Last author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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冬眠中の低温・低力学負荷環境における心筋細胞のT管膜構造の維持 Invited
氏原 嘉洋，寺島 丈壱
8 ( 2 ) 80 - 83 （「月刊細胞，55(14)，67-69」掲載記事の転載） 2024.02
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media) Publisher：北隆館
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冬眠中の低温・低力学負荷環境における心筋細胞のT管膜構造の維持
氏原 嘉洋，寺島 丈壱
2023.11
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
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Afternoon Tea 「工業大学での生理学」
氏原嘉洋
84 ( 4 ) 94 - 95 2022.11
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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Oxygen environment and cardiac regeneration
48 ( 10 ) 30 - 33 2022.09
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
Presentations
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電圧負荷に伴う膜損傷のSHG光イメージング
吉田菜都，氏原嘉洋，杉田修啓，重松大輝，中村匡徳
日本機械学会 第35回バイオフロンティア講演会 2024.12 日本機械学会バイオエンジニアリング部門
Event date： 2024.12
Language：Japanese Presentation type：Oral presentation (general)
Venue：横浜 Country：Japan
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心筋細胞の適応メカニズムの解明に向けた力学特性解析：バイオメカニクス/メカノバイオロジーの視点から Invited
氏原 嘉洋
CVMW2024 心血管代謝週間 2024.12 日本機械学会
Event date： 2024.12
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
Venue：東京 Country：Japan
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Determining Elastic Properties of Vascular Tissue Using Acoustic Impedance Measurements Invited International conference
S. Morodomi, K. Ito, S. Maegawa, Y. Ujihara, S. Sugita, and M. Nakamura
17th International Symposium on Nanomedicine 2024.12
Event date： 2024.12
Language：English Presentation type：Poster presentation
Venue：Nagoya Country：Japan
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Predicting Thrombus Formation in Stanford Type B Aortic Dissection: A Simulation-Based Study on the Effect of Shear Rate Thresholds on False Lumen Thrombosis International conference
S. Imada, K. Komiya, Y. Ujihara, S. Sugita, M. Nakamura
17th International Symposium on Nanomedicine 2024.12
Event date： 2024.12
Language：English Presentation type：Poster presentation
Venue：Nagoya Country：Japan
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The effect of circumferential stretching on MMP2 and MMP9 expression in the aortas International conference
M. Terada, Y. Ujihara, M. Nakamura and S. Sugita
17th International Symposium on Nanomedicine 2024.12
Event date： 2024.12
Language：English Presentation type：Poster presentation
Country：Japan
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Spatial-Temporal Membrane Fluidity Measurement During Cardiomyocytes Maturation International conference
Yuga Yamada, Joichi Terashima, Hiroshi Y. Yoshikawa, Yoshihiro Ujihara, Takahisa Matsuzaki
15th Korea-Japan Cancer Aging Symposium
Event date： 2024.11
Language：English Presentation type：Poster presentation
Venue：Ajou University, Suwon Country：Korea, Republic of
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Comparative Biomechanical Analysis of Ventricular Passive Mechanical Properties in Amphibians: Anurans and Pre- and Post-Metamorphic Salamanders (Ambystoma andersoni) International conference
Megumi Ito, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura
2024 biomedical engineering society annual meeting 2024.10
Event date： 2024.10
Language：English Presentation type：Poster presentation
Venue：Baltimore, MD Country：United States
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ステントグラフト末端新規内膜亀裂 (dSINE) の発症機序解明を目的とした計算力学的検討
師富真吏，岡村誉，氏原嘉洋，杉田修啓，中村匡徳
第16回血流会 2024.10 血流会
Event date： 2024.10
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京 Country：Japan
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膜流動性に基づく心筋細胞の時空間計測
山田 悠雅, 吉川 洋史, 氏原 嘉洋, 松﨑 賢寿
第85回応用物理学会秋季学術講演会 2024.09
Event date： 2024.09
Language：Japanese Presentation type：Poster presentation
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走査型超音波顕微鏡による血管組織試料のヤング率推定
師富真吏，氏原嘉洋，杉田修啓，中村匡徳
生体医工学シンポジウム2024 2024.09 日本生体医工学会
Event date： 2024.09
Language：Japanese Presentation type：Poster presentation
Venue：東京 Country：Japan
Awards
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令和3年度科学技術分野の文部科学大臣表彰 若手科学者学者賞
2021.04 文部科学省
氏原 嘉洋
Award type：International academic award (Japan or overseas) Country：Japan
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2023年度名古屋工業大学教員評価優秀賞
2024.06 名古屋工業大学
Country：Japan
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2023 JBSE Papers of the Year
2024.05 Journal of Biomechanical Science and Engineering Improvement in the precision of capillary refill time measurements for diagnosing hypovolemic status
Shukei SUGITA, Takato MIZUNO, Yoshihiro UJIHARA, Masanori NAKAMURA
Award type：Honored in official journal of a scientific society, scientific journal
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優秀ポスター表彰
2024.05 日本機械学会第36回バイオエンジニアリング講演会 脳動静脈奇形塞栓術の手技トレーニング用モデルの設計開発
一ノ瀬 花奈，後藤 峻作，西堀 正洋，氏原 嘉洋，杉田 修啓，泉 孝嗣，中村 匡徳
Award type：Award from Japanese society, conference, symposium, etc.
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優秀ポスター表彰
2024.05 日本機械学会第36回バイオエンジニアリング講演会 ラット心筋細胞のT 管膜形成過程における細胞形態と脂質成分の変化
剣持 唯舞，長尾 耕治郎，杉田 修啓，中村 匡徳，氏原 嘉洋
Award type：Award from Japanese society, conference, symposium, etc.
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Best Poster Award
2023.11
Award type：Award from international society, conference, symposium, etc. Country：Malaysia
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第3回イベリアトゲイモリ研究会 ポスター優秀賞
2022.09 イベリアトゲイモリ研究会 上陸による脊椎動物の心臓進化の解明に向けた生息環境の異なる両生類（カエル）心室の力学特性の評価～イベリアトゲイモリへの展開～
伊藤 愛, 杉田 修啓, 中村 匡徳, 氏原 嘉洋
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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Outstanding Abstract Runners-up Award at the AP Biomech 2021
2021.12 JSME Bioengineering Division
Takato Goto, Koki Nishitsuji, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara
Award type：Award from international society, conference, symposium, etc. Country：Japan
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Outstanding Abstract Award at the AP Biomech 2021
2021.12 JSME Bioengineering Division
Hiroomi KAIDA, Aika YAMAWAKI-OGATA, Yoshihiro UJIHARA Masanori NAKAMURA, Yuji NARITA, Shukei SUGITA
Award type：Award from international society, conference, symposium, etc. Country：Japan
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Outstanding Abstract Award at the AP Biomech 2021
2021.12 JSME Bioengineering Division
Megumi Ito, Mizuna Shibayama, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara
Award type：Award from international society, conference, symposium, etc. Country：Japan
Scientific Research Funds Acquisition Results
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冷たい哺乳類はどのように心筋細胞の構造を維持しているのか？～心不全治療への応用～
Grant number：24K22378 2024.07 - 2027.03
科学研究費補助金 挑戦的研究（萌芽）
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
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「しなやかさ生物学」の創成に向けた総括研究
Grant number：23H03854 2023.04 - 2026.03
科学研究費補助金 学術変革領域研究(B)
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
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膜臨界場の力学的定量化と特殊膜構造に依存したしなやかさの評価
Grant number：23H03855 2023.04 - 2026.03
科学研究費補助金 学術変革領域研究(B)
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
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冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出
2022.07 - 2024.03
科学研究費補助金 挑戦的萌芽研究
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
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哺乳類心筋細胞のT管膜構造の維持機構の解明と進化的意義の探求
2021.04 - 2025.03
科学研究費補助金 基盤研究(B)
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
Other External Funds
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脊椎動物の進化に伴う心筋細胞核の力学特性の変遷：そのメカニズム、意義、および代償の包括的理解
2024.09 - 2029.03
公益財団法人 武田科学振興財団 2024年度 ライフサイエンス研究助成
Authorship：Principal investigator Grant type：Competitive
Grant amount：\2000000
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鳥類心筋細胞の高出力を生み出す仕組みの解明
2023.04 - 2025.03
民間財団等 公益財団法人 稲盛財団 2024年度稲盛研究助成
氏原 嘉洋
Authorship：Principal investigator Grant type：Competitive
Committee Memberships
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日本機械学会東海学生会 顧問会委員
2024.04
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日本機械学会 第36回バイオエンジニアリング講演会 幹事
2023 - 2024.05
Committee type：Academic society
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日本機械学会 第32回バイオフロンティア講演会 幹事
2021.10 - 2022.01
Committee type：Academic society
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日本機械学会 バイオエンジニアリング部門 広報委員
2021 - 2022
Committee type：Academic society
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日本機械学会 バイオエンジニアリング部門 生体機能の解明とその応用に関する研究会 幹事
2019.05
Committee type：Academic society
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日本機械学会 バイオエンジニアリング部門 若手による次世代戦略委員会 幹事
2017.10 - 2021.03
Committee type：Academic society
Social Activities
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大変形時の細胞や細胞核丸ごとの硬さ評価技術
Role(s)： Informant, Demonstrator
名工大テクノフェア 2021.11
Media Coverage
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心臓が動く仕組み 機械工学で、心臓の「しなやかさ」の秘密を紐解く Internet
河合塾 みらいぶっく https://miraibook.jp/researcher/w23042 2024.06
Author：Myself