UJIHARA Yoshihiro

写真a

Affiliation Department

電気・機械工学科 機械工学分野
工学専攻 機械工学プログラム

Title

Associate Professor

External Link

Degree

  • 博士(工学) ( 2011.03   大阪大学 )

  • 修士(工学) ( 2008.03   大阪大学 )

  • 学士(工学) ( 2006.03   大阪大学 )

From School

  • Osaka University   Faculty of Engineering Science   Graduated

    2002.04 - 2006.03

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    Country:Japan

From Graduate School

  • Osaka University   Graduate School, Division of Engineering Science   Doctor's Course   Completed

    2008.04 - 2011.03

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    Country:Japan

  • Osaka University   Graduate School, Division of Engineering Science   Master's Course   Completed

    2006.04 - 2008.03

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    Country:Japan

External Career

  • Kawasaki Medical School   Lecturer

    2018.04 - 2018.09

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    Country:Japan

  • Kawasaki Medical School   Assistant Professor

    2011.04 - 2018.03

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    Country:Japan

Professional Memberships

  • 日本進化学会

    2020.09

  • 生物物理学会(Biophysical Society)

    2017.10

  • 日本生理学会

    2013.10

  • 日本生体医工学会

    2011.04

  • 日本機械学会

    2006.07

 

Papers

  • Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure Reviewed International journal

    Yoshihiro Ujihara, Motoi Kanagawa, Satoshi Mohri, Satomi Takatsu, Kazuhiro Kobayashi, Tatsushi Toda, Keiji Naruse, Yuki Katanosaka

    Nature Communications   10   1 - 17   2019.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-019-13623-2

  • Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodeling Reviewed International journal

    Ujihara Y, Iwasaki K, Takatsu S, Hashimoto K, Naruse K, Mohri S, Katanosaka Y

    Cardiovascular Research   111 ( 4 )   348 - 361   2016.09

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/cvr/cvw113

  • Proposed spring network cell model based on a minimum energy concept Reviewed International journal

    Ujihara Y, Nakamura M, Miyazaki H, Wada S

    Annals of Biomedical Engineering   38 ( 4 )   1539 - 1538   2010.04

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10439-010-9930-8

  • Relationships among capillary refill time, peripheral blood flow rate, and fingertip temperature: advances in peripheral artery contractility diagnosis Reviewed International journal

    Sorataro Shibata, Yoshihiro Ujihara, Masanori Nakamura, and Shukei Sugita

    Journal of Biomechanical Engineering   147 ( 2 )   021005   2025.02

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1115/1.4067209

  • Phenotypic Plasticity of Vascular Smooth Muscle Cells in Aortic Dissection: Insights from Ex Vivo Flow Exposure Studies Reviewed International journal

    Iwata S, Ujihara Y, Sugita S, Nakamura M

    Journal of Biorheology   39   2024.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Probing mechanical properties through acoustic impedance in cultured smooth muscle cells with cytoskeletal disruption using scanning acoustic microscopy Reviewed International journal

    Yoshihiro Ujihara, Shota Watanabe, Shinri Morodomi, Shukei Sugita, Masanori Nakamura

    Journal of Biorheology   39   2024.12

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Stress Fiber Strain is Zero in Normal Aortic Smooth Muscle, Elevated in Hypertensive Stretch, and Minimal in Wall Thickening Rats Reviewed

    14   29731   2024.11

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  • Finite element analysis and computational fluid dynamics to elucidate the mechanism of distal stent graft-induced new entry after frozen elephant trunk technique Reviewed International journal

    Morodomi S, Okamura H, Ujihara Y, Sugita S, Nakamura M

    European Journal of Cardio-Thoracic Surgery   2024.10

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics Reviewed International journal

    Ken Hashimoto, Momoko Ohira, Aya Kodama, Misaki Kimoto, Mariko Inoue, Shigenobu Toné, Yuu Usui, Akira Hanashima, Takato Goto, Yuhei Ogura, Yoshihiro Ujihara, Satoshi Mohri

    Scientific Reports   14 ( 1 )   13727   2024.06

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-024-64608-1

  • Mathematical modeling and experimental analysis of the relationship between ventricular size and diastolic function of trabecular ventricles Reviewed International journal

    Megumi Ito, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura

    37 ( 2 )   96 - 104   2023.11

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books and Other Publications

  • A mechanical cell model and its application to cellular biomechanics

    Ujihara Y, Nakamura M, Wada S( Role: Joint author)

    In Tech  2011 

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    Language:eng   Book type:Scholarly book

  • Effects of cytoskeletal structures on elastic and viscoelastic properties of cells in soft tissues

    Matsumoto T, Nagayama K, Miyazaki H, Ujihara Y( Role: Joint author)

    World Scientific Publishers  2007 

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    Language:eng   Book type:Scholarly book

Misc

  • Predictive Methods for Thrombus Formation in the Treatment of Aortic Dissection and Cerebral Aneurysms: A Comprehensive Review Reviewed

    Kenji Komiya, Shuta Imada, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura

    Bioengineering   11 ( 9 )   871   2024.08

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: 10.3390/bioengineering11090871

    Other Link: https://www.mdpi.com/2306-5354/11/9/871

  • 心筋細胞の特殊膜構造から探る哺乳類と鳥類の心臓の違い: カルシウム濃度管理と心臓の「しなやかさ」 Invited Reviewed

    氏原 嘉洋

    49 ( 2 )   82 - 86   2024.03

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    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: https://doi.org/10.5360/membrane.49.82

  • 冬眠中の低温・低力学負荷環境における心筋細胞のT管膜構造の維持 Invited

    氏原 嘉洋,寺島 丈壱

    8 ( 2 )   80 - 83 (「月刊細胞,55(14),67-69」掲載記事の転載)   2024.02

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    Authorship:Lead author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:北隆館  

  • 冬眠中の低温・低力学負荷環境における心筋細胞のT管膜構造の維持

    氏原 嘉洋,寺島 丈壱

    2023.11

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    Authorship:Lead author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • Afternoon Tea 「工業大学での生理学」

    氏原嘉洋

    84 ( 4 )   94 - 95   2022.11

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Oxygen environment and cardiac regeneration

    48 ( 10 )   30 - 33   2022.09

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

Presentations

  • 電圧負荷に伴う膜損傷のSHG光イメージング

    吉田菜都,氏原嘉洋,杉田修啓,重松大輝,中村匡徳

    日本機械学会 第35回バイオフロンティア講演会  2024.12  日本機械学会バイオエンジニアリング部門

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    Event date: 2024.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  • 心筋細胞の適応メカニズムの解明に向けた力学特性解析:バイオメカニクス/メカノバイオロジーの視点から Invited

    氏原 嘉洋

    CVMW2024 心血管代謝週間  2024.12  日本機械学会

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    Event date: 2024.12

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:東京   Country:Japan  

  • Determining Elastic Properties of Vascular Tissue Using Acoustic Impedance Measurements Invited International conference

    S. Morodomi, K. Ito, S. Maegawa, Y. Ujihara, S. Sugita, and M. Nakamura

    17th International Symposium on Nanomedicine  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya   Country:Japan  

  • Predicting Thrombus Formation in Stanford Type B Aortic Dissection: A Simulation-Based Study on the Effect of Shear Rate Thresholds on False Lumen Thrombosis International conference

    S. Imada, K. Komiya, Y. Ujihara, S. Sugita, M. Nakamura

    17th International Symposium on Nanomedicine  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya   Country:Japan  

  • The effect of circumferential stretching on MMP2 and MMP9 expression in the aortas International conference

    M. Terada, Y. Ujihara, M. Nakamura and S. Sugita

    17th International Symposium on Nanomedicine  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  • Spatial-Temporal Membrane Fluidity Measurement During Cardiomyocytes Maturation International conference

    Yuga Yamada, Joichi Terashima, Hiroshi Y. Yoshikawa, Yoshihiro Ujihara, Takahisa Matsuzaki

    15th Korea-Japan Cancer Aging Symposium 

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    Event date: 2024.11

    Language:English   Presentation type:Poster presentation  

    Venue:Ajou University, Suwon   Country:Korea, Republic of  

  • Comparative Biomechanical Analysis of Ventricular Passive Mechanical Properties in Amphibians: Anurans and Pre- and Post-Metamorphic Salamanders (Ambystoma andersoni) International conference

    Megumi Ito, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura

    2024 biomedical engineering society annual meeting  2024.10 

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    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:Baltimore, MD   Country:United States  

  • ステントグラフト末端新規内膜亀裂 (dSINE) の発症機序解明を目的とした計算力学的検討

    師富真吏,岡村誉,氏原嘉洋,杉田修啓,中村匡徳

    第16回血流会  2024.10  血流会

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  • 膜流動性に基づく心筋細胞の時空間計測

    山田 悠雅, 吉川 洋史, 氏原 嘉洋, 松﨑 賢寿

    第85回応用物理学会秋季学術講演会  2024.09 

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    Event date: 2024.09

    Language:Japanese   Presentation type:Poster presentation  

  • 走査型超音波顕微鏡による血管組織試料のヤング率推定

    師富真吏,氏原嘉洋,杉田修啓,中村匡徳

    生体医工学シンポジウム2024  2024.09  日本生体医工学会

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    Event date: 2024.09

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

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Awards

  • 令和3年度科学技術分野の文部科学大臣表彰 若手科学者学者賞

    2021.04   文部科学省  

    氏原 嘉洋

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • 2023年度名古屋工業大学教員評価優秀賞

    2024.06   名古屋工業大学  

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    Country:Japan

  • 2023 JBSE Papers of the Year

    2024.05   Journal of Biomechanical Science and Engineering   Improvement in the precision of capillary refill time measurements for diagnosing hypovolemic status

    Shukei SUGITA, Takato MIZUNO, Yoshihiro UJIHARA, Masanori NAKAMURA

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    Award type:Honored in official journal of a scientific society, scientific journal 

  • 優秀ポスター表彰​

    2024.05   日本機械学会第36回バイオエンジニアリング講演会   脳動静脈奇形塞栓術の手技トレーニング用モデルの設計開発

    一ノ瀬 花奈,後藤 峻作,西堀 正洋,氏原 嘉洋,杉田 修啓,泉 孝嗣,中村 匡徳

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    Award type:Award from Japanese society, conference, symposium, etc. 

  • 優秀ポスター表彰​

    2024.05   日本機械学会第36回バイオエンジニアリング講演会   ラット心筋細胞のT 管膜形成過程における細胞形態と脂質成分の変化

    剣持 唯舞,長尾 耕治郎,杉田 修啓,中村 匡徳,氏原 嘉洋

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    Award type:Award from Japanese society, conference, symposium, etc. 

  • Best Poster Award

    2023.11  

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    Award type:Award from international society, conference, symposium, etc.  Country:Malaysia

  • 第3回イベリアトゲイモリ研究会 ポスター優秀賞

    2022.09   イベリアトゲイモリ研究会   上陸による脊椎動物の心臓進化の解明に向けた生息環境の異なる両生類(カエル)心室の力学特性の評価~イベリアトゲイモリへの展開~

    伊藤 愛, 杉田 修啓, 中村 匡徳, 氏原 嘉洋

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • Outstanding Abstract Runners-up Award at the AP Biomech 2021

    2021.12   JSME Bioengineering Division  

    Takato Goto, Koki Nishitsuji, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • Outstanding Abstract Award at the AP Biomech 2021

    2021.12   JSME Bioengineering Division  

    Hiroomi KAIDA, Aika YAMAWAKI-OGATA, Yoshihiro UJIHARA Masanori NAKAMURA, Yuji NARITA, Shukei SUGITA

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • Outstanding Abstract Award at the AP Biomech 2021

    2021.12   JSME Bioengineering Division  

    Megumi Ito, Mizuna Shibayama, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

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Scientific Research Funds Acquisition Results

  • 冷たい哺乳類はどのように心筋細胞の構造を維持しているのか?~心不全治療への応用~

    Grant number:24K22378  2024.07 - 2027.03

    科学研究費補助金  挑戦的研究(萌芽)

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

  • 「しなやかさ生物学」の創成に向けた総括研究

    Grant number:23H03854   2023.04 - 2026.03

    科学研究費補助金  学術変革領域研究(B)

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

  • 膜臨界場の力学的定量化と特殊膜構造に依存したしなやかさの評価

    Grant number:23H03855   2023.04 - 2026.03

    科学研究費補助金  学術変革領域研究(B)

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

  • 冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出

    2022.07 - 2024.03

    科学研究費補助金  挑戦的萌芽研究

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

  • 哺乳類心筋細胞のT管膜構造の維持機構の解明と進化的意義の探求

    2021.04 - 2025.03

    科学研究費補助金  基盤研究(B)

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

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Other External Funds

  • 脊椎動物の進化に伴う心筋細胞核の力学特性の変遷:そのメカニズム、意義、および代償の包括的理解

    2024.09 - 2029.03

    公益財団法人 武田科学振興財団  2024年度 ライフサイエンス研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2000000

  • 鳥類心筋細胞の高出力を生み出す仕組みの解明

    2023.04 - 2025.03

    民間財団等  公益財団法人 稲盛財団 2024年度稲盛研究助成 

    氏原 嘉洋

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    Authorship:Principal investigator  Grant type:Competitive

 

Committee Memberships

  • 日本機械学会東海学生会   顧問会委員  

    2024.04   

  • 日本機械学会   第36回バイオエンジニアリング講演会 幹事  

    2023 - 2024.05   

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    Committee type:Academic society

  • 日本機械学会   第32回バイオフロンティア講演会 幹事  

    2021.10 - 2022.01   

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    Committee type:Academic society

  • 日本機械学会   バイオエンジニアリング部門 広報委員  

    2021 - 2022   

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    Committee type:Academic society

  • 日本機械学会   バイオエンジニアリング部門 生体機能の解明とその応用に関する研究会 幹事  

    2019.05   

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    Committee type:Academic society

  • 日本機械学会   バイオエンジニアリング部門 若手による次世代戦略委員会 幹事  

    2017.10 - 2021.03   

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    Committee type:Academic society

Social Activities

  • 大変形時の細胞や細胞核丸ごとの硬さ評価技術

    Role(s): Informant, Demonstrator

    名工大テクノフェア  2021.11

Media Coverage

  • 心臓が動く仕組み 機械工学で、心臓の「しなやかさ」の秘密を紐解く Internet

    河合塾  みらいぶっく  https://miraibook.jp/researcher/w23042  2024.06

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    Author:Myself