FURUTANI Yuji

写真a

Affiliation Department

生命・応用化学科 生命・物質化学分野
工学専攻 生命・物質化学プログラム
Opto-Biotechnology Research Center

Title

Associate Professor

Contact information

Contact information

Homepage

http://biophys-molsci.web.nitech.ac.jp/index.html

External Link

Degree

  • 博士(理学) ( 2004.03   京都大学 )

  • 修士(理学) ( 2001.03   京都大学 )

  • 学士(理学) ( 1999.03   京都大学 )

Research Areas

  • Nanotechnology/Materials / Bio chemistry

  • Life Science / Biophysics

  • Nanotechnology/Materials / Fundamental physical chemistry

From School

  • Kyoto University   Faculty of Science   Graduated

    1993.04 - 1999.03

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    Country:Japan

From Graduate School

  • Kyoto University   Graduate School, Division of Natural Science   Doctor's Course   Completed

    2001.04 - 2004.03

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    Country:Japan

  • Kyoto University   Graduate School, Division of Natural Science   Master's Course   Completed

    1999.04 - 2001.03

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    Country:Japan

External Career

  • National Institutes of Natural Sciences, Institute for Molecular Science   Associate Professor

    2009.03 - 2018.09

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    Country:Japan

  • Nagoya Institute of Technology   Graduate School of Engineering   Assistant Professor

    2007.04 - 2009.02

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    Country:Japan

  • Nagoya Institute of Technology   School of Engineering   Research Assistant

    2006.04 - 2007.03

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    Country:Japan

  • Nagoya Institute of Technology   Graduate School of Engineering   Special researcher of the Japan Society for the Promotion of Science

    2003.04 - 2006.03

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    Country:Japan

  • 科学技術振興機構   さきがけ研究員

    2011.10 - 2015.03

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    Country:Japan

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Professional Memberships

  • The Biophysical Society of Japan

    2001.05

  • Japan Society for Molecular Science

    2006.10

  • The Japanese Photochemistry Association

    2009.04

  • The Spectroscopical Society of Japan

    2005.04

  • The Chemical Society of Japan

    2005.03

 

Papers

  • SNap bond, a crucial hydrogen bond between Ser in helix 3 and Asn in helix 4, regulates the structural dynamics of heliorhodopsin Reviewed

    Toshiki Nakamura, Manish Singh, Masahiro Sugiura, Soichiro Kato, Ryo Yamamoto, Hideki Kandori, and Yuji Furutani*

    J. Mol. Biol.   436 ( 16 )   168666   2024.08

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jmb.2024.168666

  • The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4 Reviewed International coauthorship

    Tatsuki Tanaka, Shoko Hososhima, Yo Yamashita, Teppei Sugimoto, Toshiki Nakamura, Shunta Shigemura, Wataru Iida, Fumiya K. Sano1, Kazumasa Oda, Takayuki Uchihashi, Kota Katayama, Yuji Furutani, Satoshi P. Tsunoda, Wataru Shihoya*, Hideki Kandori*, Osamu Nureki*

    Mol. Cell   84 ( 18 )   3530 - 3544   2024.09

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.molcel.2024.08.016

  • Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold Reviewed International coauthorship

    Èric Catalina-Hernández, Mario López-Martín, David Masnou-Sánchez, Marco Martins, Víctor A. Lórenz-Fonfría, Francesc Jiménez-Altayó, Ute A. Hellmich, Hitoshi Inada, Antonio Alcaraz, Yuji Furutani, Alfons Nonell-Canals, Jose Luis Vázquez-Ibar, Carmen Domene, Rachelle Gaudet, and Alex Perálvarez-Marín*

    Comput. Struct. Biotechnol. J.   23   473 - 482   2023.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.csbj.2023.12.028

  • Internal Proton Transfer in the Activation of Heliorhodopsin Invited Reviewed

    Manish Singh, Masanori Hashimoto, Kota Katayama, Yuji Furutani, and Hideki Kandori

    J. Mol. Biol.   2023.09

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jmb.2023.168273

  • Concerted primary proton transfer reactions in a thermophilic rhodopsin studied by time-resolved infrared spectroscopy at high temperature Reviewed

    Kunisato Kuroi, Takashi Tsukamoto, Naoya Honda, Yuki Sudo, and Yuji Furutani

    Biochim. Biophys. Acta – Bioenergetics   1864 ( 3 )   148980   2023.08

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbabio.2023.148980

  • Protonation of Asp116 and distortion of an all-trans retinal chromophore in Krokinobacter eikastus rhodopsin 2 causes a redshift in absorption maximum upon dehydration Reviewed

    Sahoko Tomida, Akimori Wada and Yuji Furutani

    Photochem. Photobiol. Sci.   22 ( 11 )   2499 - 2517   2023.07

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s43630-023-00464-8

  • High-speed scanless entire bandwidth mid-infrared chemical imaging Reviewed International coauthorship

    Yue Zhao, Shota Kusama, Yuji Furutani, Wei-Hong Huang, Chih-Wei Luo, and Takao Fuji

    Nat. Commun.   14   3929   2023.07

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-023-39628-6

  • Covalent Bond between Lys-255 Residue and the Main Chain is Responsible for Stable Retinal Chromophore Binding and Sodium-Pumping Activity of Krokinobacter Rhodopsin 2 Reviewed International coauthorship

    Shoha Ochiai, Yuki Ichikawa, Sahoko Tomida, and Yuji Furutani

    Biochemistry   62 ( 12 )   1849 - 1857   2023.06

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.biochem.3c00168

  • Specific Zinc Binding to Heliorhodopsin Reviewed

    Masanori Hashimoto, Koichi Miyagawa, Manish Singh, Kota Katayama, Mitsuo Shoji, Yuji Furutani, Yasuteru Shigeta, and Hideki Kandori

    Phys. Chem. Chem. Phys.   25 ( 4 )   3535 - 3543   2023.01

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d2cp04718g

  • Unusual Photoisomerization Pathway in a Near-Infrared Light Absorbing Enzymerhodopsin Reviewed International coauthorship

    Masahiro Sugiura, Kazuki Ishikawa, Kota Katayama, Yuji Sumii, Rei Abe-Yoshizumi, Satoshi Tsunoda, Yuji Furutani, Norio Shibata, Leonid Brown, and Hideki Kandori*

    The Journal of Physical Chemistry Letters   13   9539 - 9543   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.jpclett.2c02334

    Other Link: https://pubs.acs.org/doi/10.1021/acs.jpclett.2c02334

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Books and Other Publications

  • Optogenetics : Light-Sensing Proteins and Their Applications in Neuroscience and Beyond

    Hisao Tsukamoto, Yuji Furutani( Role: Joint author ,  Optogenetic Modulation of Ion Channels by Photoreceptive Proteins)

    Springer Nature Singapore Pte Ltd.  2021.01  ( ISBN:978-981-15-8763-4

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    Total pages:1285   Responsible for pages:73-88   Language:eng   Book type:Scholarly book

  • Encyclopedia of Photobiology

    ( Role: Joint author)

    2016.02  ( ISBN:978-4-254-17161-7

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    Total pages:436   Responsible for pages:154-155   Language:jpn   Book type:Dictionary, encyclopedia

  • Optogenetics -Light-Sensing Proteins and Their Applications-

    Yuji Furutani( Role: Contributor ,  Molecular Mechanisms for Ion Transportation of Microbial Rhodopsins Studied by Light-Induced Difference FTIR Spectroscopy)

    Springer  2015  ( ISBN:978-4-431-55515-5

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    Total pages:409   Responsible for pages:63-76   Language:eng   Book type:Scholarly book

  • オプトジェネティクス-光工学と遺伝学による行動制御技術の最前線-

    古谷 祐詞( Role: Contributor ,  微生物型ロドプシンの光誘起イオン輸送メカニズムの解明)

    エヌ・ティー・エス  2013.04  ( ISBN:978-4-86469-071-3

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    Total pages:324   Responsible for pages:69-78   Language:jpn   Book type:Scholarly book

  • 生物物理学ハンドブック

    古谷祐詞, 神取秀樹( Role: Contributor ,  赤外・ラマン分光法)

    朝倉書店  2007.04  ( ISBN:978-4-254-17122-8

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    Total pages:680   Responsible for pages:537-539   Language:jpn   Book type:Dictionary, encyclopedia

Misc

  • 時間分解赤外分光によるレチナールタンパク質の反応計測

    古谷 祐詞

    75 ( 3 )   231 - 235   2024.06

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    Authorship:Lead author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: 10.11477/mf.2425201858

  • Ion-transporting mechanism in microbial rhodopsins: Mini-review relating to the session 5 at the 19th International Conference on Retinal Proteins Reviewed International coauthorship

    Yuji Furutani and Chii-Shen Yang

    Biophys. Physicobiol.   20   e201005   2023.01

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

    DOI: 10.2142/biophysico.bppb-v20.s005

  • Ion–protein interactions of a potassium ion channel studied by attenuated total reflection Fourier transform infrared spectroscopy Invited Reviewed International journal

    Yuji Furutani

    10 ( 2 )   235 - 239   2017.11

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Springer  

    DOI: 10.1007/s12551-017-0337-8

    Other Link: https://link.springer.com/article/10.1007/s12551-017-0337-8

  • 光誘起赤外差分光法による微生物型ロドプシンのイオン輸送機構の研究 Invited Reviewed

    古谷 祐詞

    36 ( 4 )   460 - 465   2016.01

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本レーザー医学会  

    DOI: 10.2530/jslsm.jslsm-36_0040

    Other Link: https://www.jstage.jst.go.jp/article/jslsm/36/4/36_jslsm-36_0040/_article/-char/ja

  • 急速緩衝液交換法による時間分解全反射赤外分光法の開発 Invited Reviewed

    古谷 祐詞, 木村 哲就, 岡本 基土

    54 ( 5 )   272 - 275   2014.09

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本生物物理学会  

    DOI: 10.2142/biophys.54.272

    Other Link: https://www.jstage.jst.go.jp/article/biophys/54/5/54_272/_article/-char/ja/

  • 赤外分光法による膜タンパク質の分子機構研究 Invited Reviewed

    古谷 祐詞

    8 ( 1 )   A0067   2014.09

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:分子科学会  

    DOI: 10.3175/molsci.8.A0067

    Other Link: https://www.jstage.jst.go.jp/article/molsci/8/1/8_A0067/_article/-char/ja/

  • Infrared spectroscopic studies on the V-ATPase Invited Reviewed International journal

    Hideki Kandori, Yuji Furutani, Takeshi Murata

    1847 ( 1 )   134 - 141   2014.08

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Elsevier B.V.  

    DOI: 10.1016/j.bbabio.2014.07.020

    Other Link: https://www.sciencedirect.com/science/article/pii/S0005272814005581

  • Hydrogen-bonding changes of internal water molecules upon the actions of microbial rhodopsins studied by FTIR spectroscopy Reviewed International journal

    Yuji Furutani, Hideki Kandori

    1837 ( 5 )   598 - 605   2013.09

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Elsevier B.V.  

    DOI: 10.1016/j.bbabio.2013.09.004

    Other Link: https://www.sciencedirect.com/science/article/pii/S0005272813001606

  • 全反射赤外分光法による膜タンパク質の構造機能相関研究の現状と展望 Invited Reviewed

    古谷 祐詞

    64 ( 9 )   694 - 695   2011.11

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本化学会  

    Other Link: http://www.chemistry.or.jp/journal/chemical-industry/vol64no9.html

  • An inward proton transport using Anabaena sensory rhodopsin Reviewed International journal

    Akira Kawanabe, Yuji Furutani, Kwang-Hwan Jung, Hideki Kandori

    49 ( 1 )   1 - 6   2011.03

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:Springer  

    DOI: 10.1007/s12275-011-0547-x

    Other Link: https://link.springer.com/article/10.1007/s12275-011-0547-x

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Presentations

  • Structural key elements crucial for function of Krokinobacter rhodopsin 2 and dynamics of heliorhodopsin Invited International conference

    Yuji Furutani

    20th International conference on retianl proteins 

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    Event date: 2024.11

    Presentation type:Oral presentation (invited, special)  

  • ⾚外分光計測を基軸としたオプトバイオテクノロジーの展開 Invited

    古谷祐詞

    ⽂科省・学際領域展開ハブ形成プログラム「マルチスケール量⼦−古典⽣命インターフェース研究コンソーシアム」第2回合同シンポジウム 

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    Event date: 2024.11

    Presentation type:Oral presentation (invited, special)  

    Venue:名古屋  

  • 赤外線を用いた先端計測技術によるオプトバイオサイエンスの展開 Invited

    古谷祐詞

    オプトバイオテクノロジー研究センター 2024年度シンポジウム 

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    Event date: 2024.09

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン  

  • ヘリオロドプシンの光反応ダイナミクスを制御する水素結合の発見 Invited

    古谷祐詞

    生理研研究会「生理機能の理解に向けた膜タンパク質機能ダイナミクス研究の最前線と未来開拓」 

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    Event date: 2024.09

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:岡崎  

  • 赤外分光計測による膜タンパク質のイオン輸送・透過機構の探究 Invited

    古谷祐詞

    第23回日本蛋白質科学会年会 

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    Event date: 2023.07

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋国際会議場, 名古屋  

  • Molecular Mechanisms of Microbial Rhodopsins Studied by Infrared Spectroscopy Invited International conference

    Y.Furutani

    8th Taiwan International Symposium on Raman Spectroscopy (TISRS2023) & Taiwan Association of Raman Spectroscopy (TARS) Summer Camp 

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    Event date: 2023.06

    Language:English   Presentation type:Oral presentation (invited, special)  

  • 赤外分光法による膜タンパク質の動的および静的構造変化解析 Invited

    古谷祐詞

    第18回高速分子動画オンラインセミナー  2022.02 

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    Event date: 2022.02

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン  

  • Surface-enhanced infrared spectroscopy on heliorhodopsin International conference

    Yuji Furutani

    Pacifichem 2021 

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    Event date: 2021.12

    Language:English   Presentation type:Oral presentation (general)  

    Venue:オンライン  

  • 時間分解赤外分光法から見たタンパク質の動的構造変化 Invited

    古谷 祐詞

    第94回日本生化学会大会 

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    Event date: 2021.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン  

  • 赤外分光法による膜タンパク質の分子機構研究 Invited

    古谷 祐詞

    第11回化学公開セミナー  名古屋工業大学 生命・応用化学教育類

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    Event date: 2019.06

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:名古屋(名古屋工業大学)  

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Industrial Property Rights

  • 膜タンパク質の安定化のための液体組成物および方法

    藤田恭子、溝端栄一、古谷祐詞

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    Application no:2024-025659  Date applied:2024.09

    Announcement no:2024-122906  Date announced:2024.09

Awards

  • 第3回Biophysics and Physicobiology Editors’ Choice Award

    2016   日本生物物理学会   Specific interactions between alkali metal cations and the KcsA channel studied using ATR-FTIR spectroscopy

    Yuji Furutani, Hirofumi Shimizu, Yusuke Asai, Shigetoshi Oiki, Hideki Kandori

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • 第1回BIOPHYSICS Editors’ Choice Award

    2014   日本生物物理学会   Specific interactions between alkali metal cations and the KcsA channel studied using ATR-FTIR spectroscopy

    Yuji Furutani, Tetsunari Kimura, Kido Okamoto

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • 第6回(2013年度)分子科学会奨励賞

    2013   分子科学会   赤外分光法による膜タンパク質の動作機構の解明

    古谷 祐詞

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 平成24年度分子科学研究奨励森野基金

    2012   公益信託 分子科学研究奨励森野基金   赤外分光法による膜タンパク質の情報伝達・エネルギー変換およびタンパク質機能を模倣した特異的ナノ反応場の分子機構研究

    古谷 祐詞

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    Country:Japan

  • 平成19年度名古屋工業大学職員褒賞 優秀賞

    2007   名古屋工業大学  

    古谷 祐詞

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    Country:Japan

Scientific Research Funds Acquisition Results

  • サブサイクルパルスによるバックグラウンドフリー超高感度赤外吸収分光

    Grant number:24H00451  2024.04 - 2029.03

    日本学術振興会  科学研究費助成事業  基盤研究(A)

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  • 時間分解構造解析を補完する精密顕微分光計測

    Grant number:19H05784  2019.06 - 2024.03

    日本学術振興会  科学研究費補助金  新学術領域研究

    久保 稔

  • 膜タンパク質の分子機構解明に資する新規赤外分光計測法の開発

    Grant number:26708002  2014.04 - 2018.03

    科学研究費補助金  若手研究(A)

    古谷 祐詞

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    Authorship:Principal investigator 

  • 膜電位存在下での膜タンパク質の赤外分光解析系の開発

    Grant number:26640047  2014.04 - 2017.03

    科学研究費補助金  挑戦的萌芽研究

    古谷 祐詞

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    Authorship:Principal investigator  Grant type:Competitive

  • 哺乳動物イオンチャネルの機能的発現と分子機構解析

    Grant number:24650203  2012.04 - 2014.03

    科学研究費補助金  挑戦的萌芽研究

    古谷 祐詞

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    Authorship:Principal investigator  Grant type:Competitive

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Other External Funds

  • 光駆動イオンポンプ機能を有する微生物ロドプシンの水和イオン液体による安定化と機能向上

    2024.10 - 2026.03

    公益財団法人 大幸財団  第34回自然科学系学術研究助成 

    古谷 祐詞

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    Authorship:Principal investigator  Grant type:Competitive

  • 水和イオン液体による光駆動イオン輸送タンパク質の安定化と光イオン電池の開発

    2024.09 - 2027.08

    公益財団法人 立松財団  第33回 公益財団法人 立松財団 特別研究助成(複数年) 

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    Grant type:Competitive

  • 先進的超短赤外パルス光源を用いた顕微イメージング装置の開発と生命科学への応用

    Grant number:JPMJCR17N5  2017.10 - 2023.03

    科学技術振興機構  戦略的創造研究推進事業 

    藤 貴夫

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    Grant type:Competitive

  • 様々な光エネルギー変換系における水分子の構造・機能相関解明

    Grant number:JPMJPR11QA  2011.10 - 2015.03

    科学技術振興機構  戦略的創造研究推進事業 

    古谷 祐詞

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    Grant type:Competitive

  • 光神経電子集積回路開発と機能解析・応用

    Grant number:JPMJCR09G1  2009.10 - 2011.09

    科学技術振興機構  戦略的創造研究推進事業 

    宇理須 恒雄

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    Grant type:Competitive

 

Committee Memberships

  • 日本生物物理学会   代議員  

    2023.06 - 2025.06   

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    Committee type:Academic society

  • 日本生物物理学会中部支部会   支部長  

    2023.05 - 2025.04   

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    Committee type:Academic society

  • 日本化学会   代議員  

    2021.03 - 2023.02   

  • 日本生物物理学会   理事  

    2015.06 - 2017.06   

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    Committee type:Academic society

  • 日本生物物理学会   代議員  

    2015.06 - 2016.06   

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    Committee type:Academic society

  • 分子科学会   顕彰委員会 委員  

    2014.09 - 2016.09   

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    Committee type:Academic society

  • 日本化学会   代議員  

    2013.03 - 2015.02   

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    Committee type:Academic society

Social Activities

  • 生物を探究すると化学や物理になる!?

    Role(s): Lecturer

    愛知県立名古屋南高等学校  2022.10