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Affiliation Department |
Department of Electrical and Mechanical Engineering
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Title |
Associate Professor |
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Contact information |
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External Link |
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SUGITA Shukei
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Degree
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博士（医工学） ( 2008.09 東北大学 )
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修士（工学） ( 2002.03 東北大学 )
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学士（工学） ( 2000.03 東北大学 )
Research Areas
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Life Science / Biomedical engineering
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Life Science / Biomaterials
From School
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Tohoku University Faculty of Engineering Graduated
1996.04 - 2000.03
Country：Japan
From Graduate School
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Tohoku University Biomedical Engineering Biomedical Engineering Doctor's Course Completed
2005.10 - 2008.09
Country：Japan
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Tohoku University Graduate School, Division of Engineering Master's Course Completed
2000.04 - 2002.03
Country：Japan
External Career
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独立行政法人 理化学研究所 知的財産戦略センター VCADシステム研究プログラム 細胞シミュレーションチーム 研究員
2008.10 - 2009.09
Country：Japan
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University of California, Berkeley Visiting Scholar
2019.06 - 2020.04
Country：United States
Research Career
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血管組織構造から推定する大動脈瘤の破断強度予測法の開発
Grant-in-Aid for Scientific Research
Project Year： 2010.04
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細胞骨格の張力計測に関する研究
(not selected)
Project Year： 2008.10 - 2011.03
Papers
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Polarized light retardation analysis allows for the evaluation of tension in individual stress fibers Reviewed International journal
Shukei Sugita, Masatoshi Hozaki, Tsubasa S. Matsui, Kazuaki Nagayama, Shinji Deguchi, and Masanori Nakamura
Biochemical and Biophysical Research Communications 620 49 - 55 2022.09
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1016/j.bbrc.2022.06.066
Other Link： https://www.sciencedirect.com/science/article/abs/pii/S0006291X22009196?via%3Dihub
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Decoding the effect of hydrostatic pressure on TRPV1 lower gate conformation by molecular dynamics simulation Reviewed International coauthorship International journal
Muhammad Harith Bin Zamri, Yoshihiro Ujihara, Masanori Nakamura, Mohammad R.K. Mofrad, and Shukei Sugita
International Journal of Molecular Sciences 23 ( 13 ) 7366 2022.07
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.3390/ijms23137366
Other Link： https://www.mdpi.com/1422-0067/23/13/7366
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Direct visualization of interstitial flow distribution in aortic walls Reviewed International journal
Wataru Fukui, Yoshihiro Ujihara, Masanori Nakamura, and Shukei Sugita
Scientific Reports 12 5381 2022.03
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1038/s41598-022-09304-8
Other Link： https://www.nature.com/articles/s41598-022-09304-8
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Decrease in Ca2+ Concentration in Quail Cardiomyocytes Is Faster than That in Rat Cardiomyocytes Reviewed International journal
Yuhei Ogura, Hioroaki Ito, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara
Processes 10 ( 3 ) 508 2022.03
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.3390/pr10030508
Other Link： https://www.mdpi.com/2227-9717/10/3/508
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Differences in Pressure Resistance and Tissue Structure of Ventricles between Aquatic, Semiaquatic, and Terrestrial Anura Reviewed
59 ( 6 ) 162 - 168 2021.12
Language：Japanese Publishing type：Research paper (scientific journal)
Other Link： https://www.jstage.jst.go.jp/article/jsmbe/59/6/59_162/_article/-char/ja/
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Comparison of the histology and stiffness of ventricles in Anura of different habitats Reviewed International journal
Megumi Ito, Yoshihiro Ujihara, Shukei Sugita, Masanori Nakamura
Journal of Biological Physics 2021.09
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1007/s10867-021-09579-4
Other Link： https://pubmed.ncbi.nlm.nih.gov/34515919/
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Second harmonic generation light quantifies the ratio of type III to total (I + III) collagen in a bundle of collagen fiber Reviewed International journal
Shukei Sugita, Takuya Suzumura, Akinobu Nakamura, Shinya Tsukiji, Yoshihiro Ujihara, and Masanori Nakamura
Scientific Reports 11 ( 1 ) 11874 2021.06
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1038/s41598-021-91302-3
Other Link： https://www.nature.com/articles/s41598-021-91302-3
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B16 Melanoma Cancer Cells with Higher Metastatic Potential are More Deformable at a Whole-Cell Level Reviewed International journal
Yoshihiro Ujihara, Daichi Ono, Koki Nishitsuji, Megumi Ito, Shukei Sugita, Masanori, Nakamura
Cellular and Molecular Bioengineering 2021.05
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1007/s12195-021-00677-w
Other Link： https://link.springer.com/article/10.1007/s12195-021-00677-w
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Stress fibers of the aortic smooth muscle cells in tissues do not align with the principal strain direction during intraluminal pressurization Reviewed International journal
Shukei Sugita, Naoto Mizuno, Yoshihiro Ujihara, and Masanori Nakamura
Biomechanics and Modeling in Mechanobiology 20 ( 3 ) 1003 - 1011 2021.01
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1007/s10237-021-01427-7
Other Link： https://link.springer.com/article/10.1007%2Fs10237-021-01427-7
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Three-dimensional analysis of the thoracic aorta microscopic deformation during intraluminal pressurization Reviewed International journal
Shukei Sugita, Masaya Kato, Wataru Fukui, and Masanori Nakamura
Biomechanics and Modeling in Mechanobiology 19 ( 1 ) 147 - 157 2020.02
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1007/s10237-019-01201-w
Other Link： https://link.springer.com/article/10.1007%2Fs10237-019-01201-w
Books and Other Publications
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Chapter 6.4 Tensile Properties of Smooth Muscle Cells, Elastin and Collagen Fibers, in "Vascular Engineering" (Tanishita K and Yamamoto K, eds)
T. Matsumoto, S. Sugita, and K. Nagayama（ Role： Joint author）
Springer Japan, Tokyo 2016.03 （ ISBN:4431548009 ）
Language：eng Book type：Scholarly book
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Chapter 4. "Blood Vessel" in Springer Series in Biomaterials Science and Engineering: Advances in Metallic Biomaterials Technology
Matsumoto T, Sugita S, Yaguchi T（ Role： Joint author）
Springer 2015.06 （ ISBN:978-3-662-46842-5 ）
Language：eng Book type：Scholarly book
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Analysis and techniques for controlling kinesin-driven microtubules in nanoscale transport systems, in Nano-Biomedical Engineering 2012：Proceedings of the Tohoku University Global Centre of Excellence Programme
S. Sugita, N. Sakamoto, T. Ohashi, and M. Sato（ Role： Joint author）
Imperial College Press 2012.02
Language：eng Book type：Scholarly book
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Analysis of changes in the gliding direction of kinesin-driven microtubules focusing on their length and kinesin density, in Nano-Biomedical Engineering 2009, Proceedings of the Tohoku University Global Centre of Excellence Programme
S. Sugita（ Role： Sole author）
Imperial College Press, 2009.03
Language：eng Book type：Scholarly book
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Circumferential strain distribution in rabbit thoracic aorta using novel observation technique, in Future Medical Engineering Based on Bio-nanotechnology: Proceedings of the Final Symposium of the Tohoku University 21st Century Center of Excellence Programme
S. Sugita, T. Matsumoto, and M. Sato（ Role： Joint author）
Imperial College Press 2006.11
Language：eng Book type：Scholarly book
Presentations
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血圧負荷が引き起こす大動脈壁内の力学環境―内圧負荷時の大動脈壁内観察から― Invited
杉田修啓
エラスチン・関連分子研究会 2022.11 エラスチン・関連分子研究会
Event date： 2022.11
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：大阪
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高血圧時に血管壁内平滑筋細胞のストレスファイバに外力は伝わり得るのか？ Invited
杉田修啓，川合凜太朗，水野尚登，氏原嘉洋，中村匡徳
第62回日本生体医工学会大会2023 2023.05
Event date： 2023.05
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
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冬眠時のT管膜非崩壊現象の解明に向けた非冬眠時ハムスターの単離心筋細胞の膜構造解析
寺島 丈壱，杉田 修啓，中村 匡徳，氏原 嘉洋
第62回日本生体医工学会大会2023 2023.05
Event date： 2023.05
Language：Japanese Presentation type：Poster presentation
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組織内血管平滑筋細胞のアクチンフィラメントは組織への引張負荷を細胞核に伝えるのか？
西尾香菜子，氏原嘉洋，中村匡徳，杉田修啓
第62回日本生体医工学会大会2023 2023.05
Event date： 2023.05
Language：Japanese Presentation type：Poster presentation
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Comparative evaluation of passive mechanical properties of ventricles in different habitats using Anura and Serpente
2023.03
Event date： 2023.03
Language：English Presentation type：Poster presentation
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Comparison of Ca2+ transients in cardiomyocytes isolated from quails, snakes and rats
2023.03
Event date： 2023.03
Language：English Presentation type：Poster presentation
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胸大動脈の外膜は血管半径方向の間質流速を左右するか？
田上遼，氏原嘉洋，中村匡徳，杉田修啓
ライフサポート学会第32回フロンティア講演会
Event date： 2023.03
Language：Japanese Presentation type：Oral presentation (general)
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高静水圧による膜タンパク質TRPV1の構造変化の解析
高木勝義，氏原嘉洋，中村匡徳，杉田修啓
日本機械学会東海学生会 第54回学生員卒業研究発表会講演会
Event date： 2023.03
Language：Japanese Presentation type：Oral presentation (general)
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血管組織引張時における平滑筋細胞内の核変形に対するアクチンフィラメントの影響
西尾香菜子，氏原嘉洋，中村匡徳，杉田修啓
日本機械学会東海学生会 第54回学生員卒業研究発表会講演会
Event date： 2023.03
Language：Japanese Presentation type：Oral presentation (general)
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ラット胸大動脈の外膜が間質流速に与える影響
田上遼，氏原嘉洋，中村匡徳，杉田修啓
日本機械学会東海学生会 第54回学生員卒業研究発表会講演会
Event date： 2023.03
Language：Japanese Presentation type：Oral presentation (general)
Awards
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第3回イベリアトゲイモリ研究会 ポスター優秀賞
2022.09 イベリアゲイモリ研究会 上陸による脊椎動物の心臓進化の解明に向けた生息環境の異なる両生類（カエル）心室の力学特性の評価～イベリアトゲイモリへの展開～
伊藤 愛, 杉田 修啓, 中村 匡徳, 氏原 嘉洋
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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Outstanding Abstract Award at the AP Biomech 2021
2021.12 JSME Bioengineering Division
Megumi Ito, Mizuna Shibayama, Shukei Sugita, Masanori Nakamura, Yoshihiro Ujihara
Award type：Award from international society, conference, symposium, etc. Country：Japan
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Outstanding Abstract Award at the AP Biomech 2021
2021.10 JSME Bioengineering Division
Hiroomi KAIDA, Aika YAMAWAKI-OGATA, Yoshihiro UJIHARA Masanori NAKAMURA, Yuji NARITA, Shukei SUGITA
Award type：Award from international society, conference, symposium, etc. Country：Japan
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生体医工学シンポジウム2021 ベストリサーチアワード
2021.09 日本生体医工学会
伊藤 愛, 杉田 修啓, 中村 匡徳, 氏原 嘉洋
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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第41回日本バイオレオロジー学会年会 優秀ポスター賞
2018.06 第41回日本バイオレオロジー学会年会 実行委員会 衝突流における赤血球の変形とヘモグロビン漏出
和田悠，杉田修啓，中村匡徳
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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2016 JBSE Graphics of the Year Award
2017.09 Journal of Biomechanical Science and Engineering Observations of intracellular tension dynamics of MC3T3-E1 cells during substrate adhesion using a FRET-based actinin tension sensor
Junfeng WANG, Masahiro ITO, Wenhao ZHONG, Shukei SUGITA, Tatsuo MICHIUE, Takashi TSUBOI, Tetsuya KITAGUCHI, Takeo MATSUMOTO
Award type：Honored in official journal of a scientific society, scientific journal Country：Japan
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2016 JBSE Graphics of the Year Award
2017.09 Journal of Biomechanical Science and Engineering Dynamics of actin filaments of MC3T3-E1 cells during adhesion process to substrate
Junfeng WANG, Shukei SUGITA, Kazuaki NAGAYAMA, Takeo MATSUMOTO
Award type：Honored in official journal of a scientific society, scientific journal Country：Japan
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2016 JBSE Papers of the Year Award
2017.09 Journal of Biomechanical Science and Engineering Dynamics of actin filaments of MC3T3-E1 cells during adhesion process to substrate
Junfeng WANG, Shukei SUGITA, Kazuaki NAGAYAMA, Takeo MATSUMOTO
Award type：Honored in official journal of a scientific society, scientific journal Country：Japan
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2014年度 ライフサポート学会 論文賞
2014.09 ライフサポート学会
杉田修啓，松本健郎，佐藤正明
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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Poster Award, The 4th Japan-Switzerland Workshop on Biomechanics
2014.09 The Scientific Committee of the 4th Japan-Switzerland Workshop on Biomechanics
Shukei Sugita, Vardoulis Orestis, Nikolaos Stergiopulos, Takeo Matsumoto
Award type：Award from international society, conference, symposium, etc. Country：Japan
Scientific Research Funds Acquisition Results
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冬眠中の心筋細胞のT管膜維持機構の解明による革新的心不予防法の創出
2022.07 - 2024.03
科学研究費補助金 挑戦的研究（萌芽）
氏原嘉洋
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血管組織内微視的力学場の定量による瘤発生機構解明と力学環境操作による病理応答制御
2022.04 - 2027.03
基盤研究(A)
中村匡徳
Authorship：Coinvestigator(s) Grant type：Competitive
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光学-分子動力学計算融合による細胞膜損傷の分子レベルでの理解と定量化技術の開発
2021.07
科学研究費補助金 挑戦的研究（萌芽）
中村匡徳
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哺乳類心筋細胞のT管膜構造の維持機構の解明と進化的意義の探求
2021.04
科学研究費補助金 基盤研究(B)
氏原嘉洋
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材料的・流体的力学的挙動による大動脈解離発症メカニズムの解明と医療応用への試み
2021.04
科学研究費補助金 基盤研究(A)
Other External Funds
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血管壁内の材料的・流体的力学挙動による大動脈解離形成原理の解明
2020.04
民間財団等 公益財団法人 立松財団令和2年度研究助成，特別研究助成
杉田修啓
Grant type：Competitive
Committee Memberships
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一般社団法人 日本機械学会 若手の会運営委員会 運営委員
2022.04 - 2023.04
Committee type：Academic society
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日本機械学会 第32回バイオフロンティア講演会 幹事
2021.04 - 2022.01
Committee type：Academic society
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日本機械学会 Journal of Biomechanical Science and Engineering Editors
2018.04
Committee type：Academic society
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日本機械学会 バイオエンジニアリング部門代議員
2017.04 - 2019.03
Committee type：Academic society
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日本機械学会 日本機械学会 第29回バイオエンジニアリング講演会 幹事
2016.04 - 2017.03
Committee type：Academic society
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日本生体医工学会 第54回日本生体医工学会大会，実行委員
2015.05
Committee type：Academic society
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日本機械学会 日本機械学会バイオエンジニアリング部門 生体機能の解明とその応用に関する研究会 幹事
2012.04 - 2019.05
Committee type：Academic society
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日本機械学会 Journal of Biomechanical Science and Engineering広報委員
2012.01 - 2018.03
Committee type：Academic society
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日本生体医工学会 バイオメカニクス研究会 HP担当幹事
2010.04 - 2021.03
Committee type：Academic society