Papers - MIYAGAWA Atsushi
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Unique, Fast, and All-or-none Click Reaction on Cyclodextrin and Amylose Reviewed
Hatsuo Yamamura,Kyohei Shimohara,Ryuji Kurata,Yusuke Fujita,Kensuke Murata,Takaaki Hayashi,Atsushi Miyagawa
Chemistry Letters 42 ( 6 ) 643 - 645 2013.06
Language：English Publishing type：Research paper (scientific journal)
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Mimicking an antimicrobial peptide polymyxin B by use of cyclodextrin Reviewed
Hatsuo Yamamura, Ken Suzuki, Kazuma Uchibori, Atsushi Miyagawa, Masao Kawai, Chie Ohmizo, Takashi Katsu
Chemical Communications 48 892 - 894 2011.12
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1039/C1CC16369H
Other Link： http://pubs.rsc.org/en/content/articlehtml/2012/cc/c1cc16369h
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Promiscuous activity of ER glucosidase II discovered through donor specificity analysis of UGGT Reviewed
Atsushi Miyagawa et al.
Biochemical and Biophysical Research Communications 403 ( 3-4 ) 322 - 328 2010.12
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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g-Cyclodextrins possessing an azido group and a triisopropylbenzenesulfonyl group as useful synthetic and authentic intermediates for unsymmetrically functionalized derivatives Reviewed
Yoshihide Himeno, Atsushi Miyagawa, Masao Kawai, Hatsuo Yamamura
Tetrahedron 65 ( 45 ) 9474 - 9480 2009.11
Language：English Publishing type：Research paper (scientific journal)
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gamma-Cyclodextrins possessing an azido group and a triisopropylbenzenesulfonyl group as useful synthetic and authentic intermediates for unsymmetrically functionalized derivatives Reviewed
Yoshihide Himeno, Atsushi Miyagawa, Masao Kawai, Hatsuo Yamamura
TETRAHEDRON 65 ( 45 ) 9474 - 9480 2009.11
Language：English Publishing type：Research paper (scientific journal) Publisher：PERGAMON-ELSEVIER SCIENCE LTD
Seven isomers of cyclomaltooctaose (gamma-cyclodextrin) whose C6s were unsymmetrically disubstituted with both an azido group and an arenesulfonyloxy group were prepared and each of them was isolated by reversed phase chromatography. The assignment of the modified positions in each regioisomers was unambiguously performed by chemical correlation with the authentic compounds and chemical conversion to the 3,6-anhydro derivatives followed by high-resolution 2D-(1)H NMR (COSY, TOCSY, and HO-HAHA) analyses. The compounds are versatile synthetic and authentic intermediates to prepare sophisticated derivatives with two different functionalities at desired positions on the molecule for supramolecular chemistry. (C) 2009 Elsevier Ltd. All rights reserved.
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Development of Membrane Filter with Oligosaccharide Immobilized by Click Chemistry for Influenza Virus Adsorption Reviewed
Tomohisa Kato, Atsushi Miyagawa, Maria Carmelita Z. Kasuya, Kenichi Hatanaka
The Open Chemical and Biomedical Methods Journal 2 13 - 17 2009.04
Language：English Publishing type：Research paper (scientific journal)
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Elimination Filter for Verotoxins -Highly Adsorbing by Glycoconjugate Polymer- Reviewed
A. Miyagawa, MC. Kasuya, K. Hatanaka
Chemistry Letters 37 ( 4 ) 438 - 439 2008.03
Language：English Publishing type：Research paper (scientific journal)
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Purification by Centrifugal Partition Chromatography of amphiphilic compounds, glycolipids and pseudo-glycolipids synthesized by using cells Reviewed
T. Kato, A. Miyagawa, MC. Kasuya, A. Ito, K. Hatanaka
Journal of Chromatography A 1178 ( 1-2 ) 154 - 159 2008.01
Language：English Publishing type：Research paper (scientific journal)
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Alternative methods of globotrioside production using Vero cells a microcarrier system procedure Reviewed
A. Miyagawa, MC. Kasuya, K. Hatanaka
Chemistry Central Journal 1 26 2007.11
Language：English Publishing type：Research paper (scientific journal)
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Alternative methods of globotrioside production using Vero cells: a microcarrier system procedure Reviewed
Atsushi Miyagawa, Maria Carmelita Z. Kasuya, Kenichi Hatanaka
CHEMISTRY CENTRAL JOURNAL 1 26 2007.11
Language：English Publishing type：Research paper (scientific journal) Publisher：BIOMED CENTRAL LTD
Background: Glycolipids are one component of cell membranes, and are found most prevalently at the surface of the plasma membrane. Animal cells take in amphipathic glycosides, which are later glycosylated after assimilation in biosynthetic pathways. Gycosylated glycosides are released outside of cells to the surrounding culture medium. This represents an accessible method of obtaining complex glycosides.
Results: Vero cells are sensitive to Shiga toxins and are known to express the glycosides globotriaosyl ceramide (Gb3) and globotetraosyl ceramide (Gb4) on the surface of the plasma membrane. By administering amphipathic lactosides to Vero cells, the above mentioned glycolipids could be produced by the action of cellular enzymes. In our study, the optimum conditions (seeded cell number, incubated time period, 12-azidododecyl lactoside concentration and medium volume) for the production of Gb3 analogue were investigated. The 87.9 mu g/100 mm dish (11.7% yield) Gb3 analogue was produced under appropriate conditions. The large-scale culture of Vero cells using a microcarrier culture method with repetitions produced about 30 mg of the Gb3 analogue.
Conclusion: The mass production of glycosides in Vero cells was carried out on a microcarrier with repeated administration of 12-azidododecyl lactoside. The results indicated that the use of both a microcarrier culture and repetition were highly effective in the production of Gb3, Gb4 and sialyl lactoside (GM3) type-oligosaccharides. -
Inhibitory effects of glycopolymers having globotriose and/or lactose on cytotoxicity of Shiga toxin 1 Reviewed
A. Miyagawa, MC. Kasuya, K. Hatanaka
Carbohydrate Polymers 67 ( 2 ) 260 - 264 2007.01
Language：English Publishing type：Research paper (scientific journal)
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Applications of Immobilized Glycopolymers -Development and potentiality of the adsorption filter for influenza virus Reviewed
A. Miyagawa, M. Nakane, K. Hatanaka
seisan kenkyu 59 ( 2 ) 110 - 113 2007.01
Language：English Publishing type：Research paper (scientific journal)
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糖鎖高分子の医療用途を考える
宮川 淳、畑中 研一
未来材料 6 ( 7 ) 32 - 37 2006.07
Language：Japanese Publishing type：Research paper (other academic)
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Structural Analysis of the Interaction between Shiga Toxin B Subunits and Linear Polymers Bearing Clustered Globotriose Residues Reviewed
M. Watanabe, K. Igai, K. Matsuoka, A. Miyagawa, T. Watanabe, R. Yanoshita, Y. Samejima, D. Terunuma, Y. Natori, K. Nishikawa
Infection and Immunity 74 ( 3 ) 1984 - 1988 2006.03
Language：English Publishing type：Research paper (scientific journal)
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Immobilization of Glycoconjugate Polymers on Cellulose Membrane for Affinity Separation Reviewed
A. Miyagawa, MC. Kasuya, K. Hatanaka
Bulletin of the Chemical Society of Japan 79 ( 2 ) 348 - 356 2006.02
Language：English Publishing type：Research paper (scientific journal)
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Development of dialyzer with immobilized glycoconjugate polymers for removal of Shiga-toxin Reviewed
A. Miyagawa, M. Watanabe, K. Igai, MC. Kasuya, Y. Natori, K. Nishikawa, K. Hatanaka
Biomaterials 27 ( 17 ) 3304 - 3311 2006.02
Language：English Publishing type：Research paper (scientific journal)
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Synthesis of polyesters from 5-hydroxymethyl-2-furfural as a starting material Reviewed
K. Hatanaka, D. Yoshida, K. Okuyama, A. Miyagawa, K. Tamura, N. Sato, K. Hashimoto, M. Sagehashi, A. Sakoda
Kobunshi Ronbunshu 62 316 - 320 2005.07
Language：English Publishing type：Research paper (scientific journal)
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Syntheses of polyesters from 5-hydroxymethyl-2-furfural as a starting material Reviewed
K Hatanaka, D Yoshida, K Okuyama, A Miyagawa, K Tamura, N Sato, K Hashimoto, M Sagehashi, A Sakoda
KOBUNSHI RONBUNSHU 62 ( 7 ) 316 - 320 2005
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：SOC POLYMER SCIENCE JAPAN
Polyesters were synthesized from 5-hydroxymethyl-2-furfural (HMF), which can be prepared by pyrolysis of biomass or cellulose. 2,5-Bis (hydroxymethyl) furan (BHF), which was prepared by the reduction of HMF, and natural dicarboxylic acids such as succinic acid, fumaric acid, or maleic acid were polymerized to give polyesters. Polycondensations were carried out by two methods: one used acid chloride and the other one used a condensing reagent. Polycondensation of BHF and succinic acid gave a polymer of which the number averaged degree of polymerization was 30. NMR and IR spectra indicated that the obtained polymers have linear and regular polyesters. Copolymerization performed using the mixture of two kinds of dicarboxylic acids gave the copolymers. DSC measurements of polyesters showed the melting temperature and the grass transition temperature.
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Fluorous-tagged compound: a viable scaffold to prime oligosaccharide synthesis by cellular enzymes Reviewed
MC. Kasuya, R. Cusi, O. Ishihara, A. Miyagawa, K. Hashimoto, T. Sato, K. Hatanaka
Biochemical and Biophysical Research Communication 316 ( 3 ) 599 - 604 2004.04
Language：English Publishing type：Research paper (scientific journal)
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Synthesis of glycoconjugate polymer carrying globotriaose as artificial multivalent ligand for Shigatoxin-producing Escherichia coli O157: H7. Reviewed
A. Miyagawa, H. Kurosawa, T. Watanabe, T. Koyama, D. Terunuma, K. Matsuoka
Carbohydrate Polymers 57 441 - 450 2004.03
Language：English Publishing type：Research paper (scientific journal)
