SHIBATA Norio

写真a

Affiliation Department

Department of Life Science and Applied Chemistry
Department of Life Science and Applied Chemistry

Title

Professor

External Link

Degree

  • 博士(薬学) ( 1993.03   大阪大学 )

 

Research Career

  • 色素を用いた太陽電池の開発

    The Other Research Programs  

    Project Year: 2005.01

  • Design, Synthesis and Propaties of Phthalocyanines

    Grant-in-Aid for Scientific Research  

    Project Year: 2003.04

  • サリドマイドの研究

    The Other Research Programs  

    Project Year: 1998.01

  • Enantioselective Synthesis of Organofluorine Compounds

    Grant-in-Aid for Scientific Research  

    Project Year: 1988.04

Papers

  • KHMDS/Triglyme Cryptate as an Alternative to Phosphazene Base in Stereodivergent Pentafluoroethylation of N-Sulfinylimines Using HFC-125 Reviewed International coauthorship

    Yuji Sumii, Hiroto Iwasaki, Yamato Fujihira, Elsayed M. Mahmoud, Hiroaki Adachi, Takumi Kagawa, Dominique Cahard, Norio Shibata

    The Journal of Organic Chemistry   2022.10

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.joc.2c01821

  • Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library Reviewed International coauthorship

    Arif Nurkanto, Riyo Imamura, Yulia Rahmawati, Erwahyuni Endang Prabandari, Danang Waluyo, Takeshi Annoura, Kazuki Yamamoto, Masakazu Sekijima, Yuki Nishimura, Takayoshi Okabe, Tomoo Shiba, Norio Shibata, Hirotatsu Kojima, James Duffy, Tomoyoshi Nozaki

    Antimicrob. Agents Chemother.   66   2022.10

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1128/aac.00420-22

    DOI: 10.1128/aac.00420-22

    Other Link: https://journals.asm.org/doi/full/10.1128/aac.00420-22

  • Unusual Photoisomerization Pathway in a Near-Infrared Light Absorbing Enzymerhodopsin Reviewed International coauthorship

    Masahiro Sugiura, Kazuki Ishikawa, Kota katayama, Yuji Sumii, Rei Abe-Yoshizumi, Satoshi P.Tunoda, Yuji Furutani, Norio Shibata, Leonid S.Brown, Hideki Kandori

    The Journal of Physical Chemistry Letters   13 ( 40 )   9539 - 9543   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.jpclett.2c02334

  • Continuous-Flow Synthesis of Perfluoroalkyl Ketones via Perfluoroalkylation of Esters Using HFC-23 and HFC-125 under a KHMDS-Triglyme System Reviewed

    Yamato Fujihira, Hiroto Iwasaki, Yuji Sumii, Hiroaki Adachi, Takumi Kagawa, Norio Shibata

    Bulletin of the Chemical Society of Japan   2022.08

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1246/bcsj.20220162

  • Etherification of Fluoroarenes with Alkoxyboronic Acid Pinacol Esters via C-F Bond Cleavage Reviewed

    Jun Zhou, Bingyao Jiang, Zhengyu Zhao, Norio Shibata

    Organic Letters   24 ( 28 )   5084 - 5089   2022.07

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.2c01864

  • Synthesis of Pyridine-SF4-Isoxazolines Using the Functionality of trans-Tetrafluoro-λ6-sulfanyl Rodlike Linkers Reviewed

    Koki Maruno, Kenshiro Hada, Yuji Sumii, Osamu Nagata, Norio shibata

    Organic Letters   24 ( 21 )   3755 - 3759   2022.04

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.2c01046

  • Regioselective Synthesis of Pyridine-SF4-Methyl Ketones via Hydration of Pyridine-SF4-Alkynes Reviewed

    Kentaro Iwaki, Kazuhiro Tanagawa, Soichiro Mori, Koki Maruno, Yuji Sumii, Osamu Nagata, Norio Shibata

    Organic Letters   24 ( 18 )   3347 - 3352   2022.04

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.2c00998

    Other Link: https://pubs.acs.org/doi/10.1021/acs.orglett.2c00998

  • Ethynyl-SF4-Pyridines:Reagents for SF4-Alkynylation to Carbonyl Compouds Reviewed

    Kentaro Iwaki, Koki Maruno, Osamu Nagata, Norio Shibata

    The Journal of Organic Chemistry   87 ( 9 )   6302 - 6311   2022.04

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.joc.2c00564

    Other Link: https://pubs.acs.org/doi/10.1021/acs.joc.2c00564

  • Enantio-,Diastereo-and Regioselective Synthesis of Chiral Cyclic and Acyclic gem-Difluoromethylenes by Palladium-Catalyzed[4+2]Cycloaddition Reviewed

    Hiroto Uno, Koki kawai, Taichi Araki, Motoo Shiro, Norio Shibata

    Angew. Chem., Int. Ed.   61 ( 24 )   2022.03

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/anie.202117635

  • Synthesis of an Eccentric Electron-Deficient Fluorinated Motif,Tetrafluoro-λ6-sulfanyl gem-Difluorocyclopropenes Reviewed

    Koki Maruno, Kiyoteru Niina, Osamu Nagata, and Norio shibata

    Organic Letters   24 ( 8 )   1722 - 1726   2022.02

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.2c00358

    Other Link: https://pubs.acs.org/doi/10.1021/acs.orglett.2c00358

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Books and Other Publications

  • Development of Organoiodine Catalysis and Reagents for Synthesis of Organofluorine Compounds Reviewed

    ( Role: Joint author)

    2022.08 

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    Responsible for pages:14-30   Language:jpn   Book type:Scholarly book

    Other Link: https://www.cmcbooks.co.jp/products/detail.php?product_id=8647

  • トリフルオロメチル化合物(フローマイクロ合成の最新動向,深瀬浩一,永木愛一郎 編)

    住井裕司,柴田哲男( Role: Joint author)

    シーエムシー出版  2021.08  ( ISBN:978-4-7813-1615-4

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    Responsible for pages:第14章 pp149-168   Language:jpn   Book type:Scholarly book

  • フタロシアニンを基盤とする機能材料の開発(未来を拓く多彩な色素材料)

    森悟,柴田哲男( Role: Joint author)

    化学同人  2021.03  ( ISBN:978-4-7598-1400-2

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    Responsible for pages:p.131-145   Language:jpn   Book type:Scholarly book

  • フッ素化学を足がかりとする不凍作用物質の設計と合成

    住井裕司,柴田哲男( Role: Joint author)

    低温生物工学会誌  2021.02 

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    Responsible for pages:2020年,66巻,2号 p. 65-71   Language:jpn   Book type:Scholarly book

  • トリフルオロメチル化反応のフロー合成法への展開(フロー合成、連続生産のプロセス設計、条件設定と応用事例)

    住井裕司,柴田哲男( Role: Joint author)

    (株)技術情報協会  2020.12  ( ISBN:978-4-86104-820-3

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    Responsible for pages:第6章 第9節:pp 316-330   Language:jpn   Book type:Scholarly book

  • Fluolead (Ar-SF3) Deoxofluorination

    Benqiang Cui, Norio Shibata( Role: Joint author)

    Fluorination. Synthetic Organofluorine Chemistry., Eds. Hu J., Umemoto T., Springer, Singapore.  2020.09  ( ISBN:978-981-10-3895-2

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    Language:eng   Book type:Scholarly book

  • Emerging Fluorinated Motifs: Synthesis, Properties and Applications

    Yumeng Liang, Dominique Cahard, Norio Shibata( Role: Contributor)

    John Wiley & Sons, Inc.  2020.04  ( ISBN:978-3-527-34681-3

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    Responsible for pages:403-448   Language:eng   Book type:Scholarly book

  • サリドマイド研究のパラドックス 光学異性体の自己不均一化現象

    徳永 恵津子, 柴田 哲男( Role: Joint author)

    ファルマシア 2020 年 56 巻 4 号  2020.04 

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    Responsible for pages:330-334   Language:jpn  

  • Direct Trifluoromethylthiolation toward C(sp3)-SCF3 Compounds (Emerging Fluorinated Motifs: Synthesis, Properties and Applications, 2 Volume Set)

    Liang, Y.; Cahard, D.; Shibata, N.( Role: Joint author)

    John Wiley & Sons, Inc.  2020.04  ( ISBN:978-3-527-34681-3

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    Responsible for pages:403-448   Language:eng   Book type:Scholarly book

  • Case Studies of Aryl Sulfur Pentafluorides in Drug Development

    ( Role: Joint author)

    2020.02 

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    Language:jpn   Book type:Scholarly book

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Misc

  • 2021年に,EMBO Journal誌(Impact Factor 11.598 (2020))に報告した サリドマイドに関する論文が,2021年のダウンロード数Top20に選ばれました

    柴田哲男

    2021.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)  

    Other Link: https://www.nitech.ac.jp/research/news/9246.html

  • フッ素化合物からフッ素のみ除去へ 名古屋工業大チームが手法開発

    木村俊介, 柴田哲男

    2021.10

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  • 蛋白質PLZFを新発見-サリドマイド催奇性に関与 愛媛大学,東北大学,名古屋大学,名古屋工業大学研究グループ

    日本テレコン

    2021.02

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    Language:Japanese  

  • サリドマイド催奇性 分子メカニズム解明 愛媛大・東北大など

    科学新聞

    2021.01

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    Language:Japanese  

  • 蛋白質PLZFが関与‐サリドマイド催奇形性愛媛大学研究グループ

    薬事日報

    2021.01

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    Language:Japanese  

  • サリドマイド催奇性に関わるタンパク質PLZFを同定-愛媛大ほか

    医療NEWS

    2021.01

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    Language:Japanese  

  • サリドマイド催奇性を引き起こすタンパク質の発見~サリドマイドによる副作用のメカニズムを提唱~

    テック・アイ技術情報研究所

    2021.01

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    Language:Japanese  

  • 愛媛大・東北大・名大・名工大・AMED、サリドマイド催奇性を引き起こすタンパク質を発見

    日本経済新聞

    2021.01

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    Language:Japanese  

  • サリドマイド催奇性を引き起こすタンパク質の発見―サリドマイドによる副作用のメカニズムを提唱―

    日本医療研究開発機構

    2021.01

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    Language:Japanese  

  • NHK松山 サリドマイドの薬害作用 タンパク質で明らかに

    日本経済新聞

    2020.10

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    Language:Japanese   Publisher:NHK松山  

    NHK松山 愛媛大学 サリドマイドの薬害作用 タンパク質で明らかに」愛媛大との共同研究成果が放映された

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Presentations

  • C-F Bond: from Formation to Activation Invited International conference

    Norio Shibata

    The World Class Professor Program from September to November 2022  2022.11  Dr. Muhammad Idham Darussalam Mardjan

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    Event date: 2022.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Indonesia  

  • Design of Halogen Bond Donors Based on the Fluorine Chemistry Invited International conference

    Norio Shibata

    5th International Symposium on Halogen Bonding (ISXB5)  2022.11  Tatsuo Kaiho, Kazuaki Ishihara

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    Event date: 2022.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:kazusa Academia Park in Kisarazu (Chiba, Japan)   Country:Japan  

    Other Link: https://fiu-iodine.org/isxb5/invitation/

  • C-F Bond: From formation to activation Invited International conference

    Norio Shibata

    Scientific Seminar, University of Orléans  2022.10  Marie-Aude Hiebel

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    Event date: 2022.10

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:France  

  • C-F Bond: From formation to activation Invited

    Norio Shibata

    Scientific Seminar, University of Strasbourg   2022.09  Frederic Leroux

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    Event date: 2022.09

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:Strasbourg, France   Country:France  

  • C-F Bond: From formation to activation Invited International conference

    Norio Shibata

    Scientific Seminar, University of Versailles Saint-Quentin-en-Yvelines   2022.09  Emmanuel Magnier

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    Event date: 2022.09

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:Versailles, France   Country:France  

  • Contributions of Organofluorine Molecules to Life Science Invited International conference

    Norio Shibata

    Autumn School of the XL-Chem  2022.09  Audrey GOSSELIN (ROBINE)

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    Event date: 2022.09

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Normandie Université, Rouen (Mont Saint Aignan, France)   Country:France  

  • C-F Bond: from Formation to Activation Invited International conference

    Norio Shibata

    20th European Symposium on Fluorine Chemistry  2022.08  Thomas Braun; Sebastian Hasenstab-Riedel

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    Event date: 2022.08

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Humboldt-Universität zu Berlin (Berlin, Germany)   Country:Germany  

  • C-F Bond: From formation to activation Invited International conference

    Norio Shibata

    Scientific Seminar, Departamento de Química Orgánica, Facultad de Farmacia, Universitat de Valencia   2022.07  Jorge Escorihuela

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    Event date: 2022.07

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:Spain  

  • サリドマイドの催奇形性と自己不均一化現象 Invited

    柴田哲男

    第49回日本毒性学会学術年会  2022.06  第49回日本毒性学会

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    Event date: 2022.06 - 2022.07

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:札幌コンベンションセンター  

  • C-F Bond: From formation to activation Invited International conference

    Norio Shibata

    Scientific Seminar, ENSICAEN & Université de Caen  2022.04  Bernhard Witulski

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    Event date: 2022.04

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Country:France  

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Works

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Awards

  • Chair of Excellence

    2022.04   LabEx SynOrg  

    柴田哲男

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    Country:France

  • Excellent Reviewer

    2021.05   Publons  

    柴田哲男

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    Country:United States

  • Fellow of Royal Society of Chemistry

    2021.05   Royal Society of Chemistry  

    柴田哲男

  • CAS REGISTRY Innovator

    2021.05   American Chemical Society  

    柴田哲男

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    Country:United States

  • ACS Award for Creative Work in Fluorine Chemistry

    2018.09   American Chemical Society  

    Norio Shibata

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    Award type:International academic award (Japan or overseas)  Country:United States

  • International Congress on Pure&Applied Chemistry(ICPAC)2018 Lecture aAward

    2018.03   INSTITUT KUMIA MALAYSIA & CAMBODIAN CHEMICAL SOCIETY  

    Norio Shibata

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    Award type:International academic award (Japan or overseas)  Country:Cambodia

  • 第51回(平成29年度)色材協会賞(論文賞)

    2017.07   一般社団法人色材協会   「グルコフラノース部位を持つ含フッ素フタロシアニンの合成と分光学的性質および光線力学的療法への展開

    柴田哲男

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • International Scientific Partnership Foundation Award (The Gold Medals “CBC-2015, St. Petersburg”)

    2015.08   International Scientific Partnership Foundation  

    Norio Shibata

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    Award type:International academic award (Japan or overseas)  Country:Russian Federation

  • CSJ Award for Creative Work in Chemical Society of Japan, 2015

    2015.03  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 名古屋工業大学特別褒章

    2014.06   名古屋工業大学  

    柴田哲男

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    Country:Japan

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Other External Funds

  • フッ素循環社会を実現するフッ素材料の精密分解

    2021.10 - 2027.03

    文部科学省  戦略的創造研究推進事業 

    柴田哲男

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    Grant type:Competitive

 

Social Activities

  • 愛知県立一宮高校SSH

    Role(s): Lecturer

    2022.12

  • 愛知県立瑞陵高等学校普通科コスモサイエンスコース

    Role(s): Lecturer

    2022.11

  • 愛知県立一宮高校SSH

    Role(s): Lecturer

    2022.10

  • 愛理県立明和高等学校SSH

    Role(s): Lecturer

    2022.06

  • 愛知県立瑞陵高等学校コスモサイエンスコース

    Role(s): Lecturer

    2021.11

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    Audience: High school students

    Type:Lecture

    講義

  • 愛知県立一宮高等学校SSH

    Role(s): Lecturer, Advisor, Demonstrator

    2021.10

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    Audience: High school students

    講義,実験

  • 愛知県立瑞陵高等学校コスモサイエンスコース

    Role(s): Lecturer

    2020.10

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    Audience: High school students

    Type:Lecture

    講義

  • 愛知県立一宮高等学校SSH

    Role(s): Lecturer, Advisor, Demonstrator

    2020.09

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    Audience: High school students

    講義,実験

Media Coverage

  • 第44回フッ素化学討論会 Internet

    日本フッ素化学会  ZOOM開催  2021.11

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    実行委員長

  • 令和3年度有機合成セミナー オンライン開催 Internet

    有機合成化学協会東海支部  ZOOM開催  2021.06

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    実行委員長

  • 名古屋工業大学医薬工連携 ― 先端医療を生み出す工学研究 オンデマンド型オンライン講座 Internet

    名古屋工業大学  2021.06

  • 令和二年度 有機合成化学協会東海支部総合講演会開催 Internet

    有機合成化学協会東海支部  ZOOM開催  2020.12

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    名古屋工業大学 平下恒久准教授とともに開催

Academic Activities

  • ACS Fall 2022, Synthetic Method in Fluorine Chemistry International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    Norio Shibata and ACS  2022.08

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    Type:Academic society, research group, etc. 

  • The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem) International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    Norio Shibata and ACS, JCS  2021.12

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    Type:Academic society, research group, etc. 

  • 第44 回フッ素化学討論会 International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    柴田哲男&日本フッ素化学会  2021.11

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    Type:Academic society, research group, etc. 

  • 令和3年度有機合成セミナー International contribution

    Role(s): Planning, management, etc., Panel moderator, session chair, etc.

    柴田哲男,日本有機合成化学協会東海支部  2021.11

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    Type:Academic society, research group, etc. 

  • 夢ナビ YUMENAVI ALL STARS登録教員

    夢ナビ  2015